Information Package / Course Catalogue
Biology of Stem Cell
Course Code: VET437
Course Type: Area Elective
Couse Group: First Cycle (Bachelor's Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 1
Prt.: 0
Credit: 1
Lab: 0
ECTS: 2
Objectives of the Course

Ability to differentiate into different cell types and self-renewal are the two most important features of stem cells. There exist different types of stem cells. The aim of this course is to provide the student with a framework to understand basic properties of stem cells, different types of stem cells, isolation and derivation of various stem cells, and potential uses of stem cells in veterinary medicine.

Course Content

Basic properties of stem cells, different stem cell types, isolation and development of stem cells in laboratory conditions, differentiation of stem cells to obtain various cell types, potential uses of stem cells in the treatment of certain diseases in veterinary medicine.

Name of Lecturer(s)
Prof. Levent KARAGENÇ
Learning Outcomes
1.Understands the basic properties of stem cells and their differences from other cells, including progenitor cells.
2.Understands the isolation, characterization of embryonal stem cells (ESC) and their use in medicine.
3.Understands the isolation, characterization and medical use of induced pluripotent stem cells (iPS) obtained from somatic cells, which have almost the same properties as ES cells.
4.Gain information about current clinical applications and potential areas of use of ESC and iPS cells in the field of regenerative medicine.
5.Gain knowledge about the stem cells specific to certain tissues (tissue specific) in the adult period, the functions and basic properties of these cells.
Recommended or Required Reading
1.Ebru Karadağ Sarı and Sevda Eliş Yıldız (2023). Stem cells and application areas. Efe Academic Publications, ISBN:9786256600867.
2.Berrin Zık (2019). General Embryology. Ezgi Bookstore.
3.Osman Hassa and Reşat N. Aşti (2003). Embryology. Ankara.
4.Jonothan Slack (2012). Stem Cells: A Very Short Introduction. Oxford Academic.
5.Mohamed Al-Rubeai ve Mariam Naciri (2014). Stem Cells and Cell Therapy. Springer.
6.Lawrence S.B. Goldstein ve Meg Schneider (2010) Stem cells for Dummies. Wiley Publishing.
7.Ratan Kumar Choudhary ve ?Shanti Choudhary (2022). Stem Cells in Veterinary Science. Springer.
8.https://stemcells.nih.gov/info/basics/stc-basics
Weekly Detailed Course Contents
Week 1 - Theoretical
The importance of gene expression in cell differentiation
Week 2 - Theoretical
Gene expression (genome, transcriptome, proteome) analysis methods
Week 3 - Theoretical
Initial cell differentiation and formation of the inner cell mass in mammalian species
Week 4 - Theoretical
Basic features of stem cells
Week 5 - Theoretical
Stem cell types
Week 6 - Theoretical
The importance of cell culture in obtaining stem cells
Week 7 - Theoretical
Isolation and characterization of embryonic stem (ES) cells
Week 8 - Theoretical
Repetition of subjects and Midterm exam
Week 9 - Theoretical
Isolation and characterization of iPS cells
Week 10 - Theoretical
Tissue-specific (adult) stem cells
Week 11 - Theoretical
The concept of microenvironment (niche) in stem cell biology and the importance of microenvironment in stem cell biology
Week 12 - Theoretical
Obtaining different cells from embryonic stem cells
Week 13 - Theoretical
Obtaining organ-like structures (Organoids) from embryonic stem cells and the uses of organoids in medicine
Week 14 - Theoretical
Uses of stem cells in veterinary medicine
Week 15 - Final Exam
Final exam
Assessment Methods and Criteria
Type of AssessmentCountPercent
Midterm Examination1%20
Final Examination1%60
Assignment2%20
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory130113
Assignment25010
Reading50210
Midterm Examination1718
Final Examination1819
TOTAL WORKLOAD (hours)50
Contribution of Learning Outcomes to Programme Outcomes
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Adnan Menderes University - Information Package / Course Catalogue
2026