Information Package / Course Catalogue - Adnan Menderes University

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Virology

Course Code	: VET318
Course Type	: Required
Couse Group	: First Cycle (Bachelor's Degree)
Education Language	: Turkish
Work Placement	: N/A

Theory	: 3
Prt.	: 2
Credit	: 4
Lab	: 0
ECTS	: 4

Objectives of the Course

The aims of this course are; 1. to inform the students about viruses (morphology, taxonomy, replications mechanism, isolation and identification of viruses), 2. to describe virus infections (Etiological, epidemiological, clinically, pathologically and diagnostically properties of these infections) 3. to inform about strategies for prevention from viral infections 4. to teach zoonotic diseases that is caused by viruses to earn the students ability to practice these virological knowledge

Course Content

This course focuses on General Virology and Viruses are important for veterinary medicine and also zoonotic viruses.

Name of Lecturer(s)

Prof. Mehmet Tolga TAN

Prof. Nural EROL

Learning Outcomes

1.	To be able to have general knowledge about viruses and virological science.
2.	To be able to name diseases, which occur or can arise in Turkey and which are important for animal and public health and in addition for diagnosis and prevention of these infections
3.	To be able to comprehend how to work in virology labors
4.	To be able to grasp criteria in sampling for the purpose of viral diagnosis; determination and selection of suitable materials, sending samples to the virology laboratories, preparation of inoculum from suspected material
5.	To be able to comprehend criteria in sampling for the purpose viral diagnosis; determination and selection of suitable materials, sending samples to the virology laboratories, preparation of inoculum from suspected material
6.	To be able to comprehend isolation or production, determination, quantification and identification of viruses and diagnostic methods for virus infection
7.	To be able to apply basic procedures for diagnostic methods in virology lab.

Recommended or Required Reading

1.	1. Burgu, I., Akça Y., (2006) Genel Viroloji, Ankara Üniversitesi Veteriner Fakültesi Yayınları, Ankara
2.	2. Burgu, I., Akça Y., (2007) Özel Viroloji, Ankara Üniversitesi Veteriner Fakültesi Yayınları, Ankara
3.	3. Murphy, F.A., Gibbs, E.P.J., Horzinek, M.C., Studdert, M.J., (1999) Veterinary Virology, Academic Press, 3. Ed., Boston, New York, Sydney, Tokyo, Toronto
4.	4. Flint S. J., Enquist, L. W., Racaniello, V.R., Skalka, A.M. (2009) Principles of Virology, ASM Press, 3. Ed., USA

Weekly Detailed Course Contents

Week 1 - Theoretical

Introduction to Virology and information about the course: Presentation of recommended books to learn virology. Importance of viruses and virology for animal and public health. History of Virology. Definition of virus: General Characters of Viruses. The Differences between viruses and other microorganisms

Week 1 - Preparation Work

Showing of movies and slides about viruses and virology.

Week 2 - Theoretical

Morphological structure of viruses, chemical composition of virions, function of virus components.

Week 2 - Preparation Work

Introduction of virology laboratory, work principles and safety in the laboratory. Information about laboratory materials. Sterilization, disinfection and antisepsis.

Week 3 - Theoretical

Viral Replications. Antiviral drugs, interference, interferon

Week 3 - Preparation Work

Diagnosis of viral infections. Criteria in sampling for the purpose to research and diagnosis; determination and selection of suitable materials, sending samples to the virology laboratories, preparation of inoculum from suspected material.

Week 4 - Theoretical

Diversity and Taxonomy of viruses

Week 4 - Preparation Work

Virus isolation. Inoculation methods in the embryonic chicken egg

Week 5 - Preparation Work

Tissue and cell cultures. Preparation of primer cell cultures.

Week 6 - Theoretical

Epidemiology, pathogenesis, immunology of virus infections and viral vaccines.

Week 6 - Preparation Work

Preservation of cell cultures. Virus inoculation in cell culture. Determining of virus replication in cell culture.

Week 7 - Theoretical

Picornaviridae and infections of picornaviruses. (Footh and Mouth disease virus, enterovirus, rhinovirus).

Week 7 - Preparation Work

Virus titration and plaque test.

Week 8 - Preparation Work

Neutralization test

Week 9 - Theoretical

Rhabdoviridae and infections of rhabdoviruses (Rabies, vesicular stomatitis and ephemeral fever viruses)

Week 9 - Preparation Work

Hemaglutination test. Showing about labor diagnostic of Rabies.

Week 10 - Theoretical

Bunyaviridae, Reoviridae and their infections (akabane, blue tongue and african horse sickness viruses, reovirus and rotavirus infections in different species)

Week 10 - Preparation Work

Agar Gel Immunodiffussion and Complement Fixation tests.

Week 11 - Theoretical

Paramyxoviridae and infections of paramyxoviruses ( Rinderpest, Peste des petits ruminants, distemper, PI-3 and respiratory syncytial viruses)

Week 11 - Preparation Work

Movie/ Slide show about Clinical symptoms, pathology and laboratory diagnosis of rinder pest.

Week 12 - Theoretical

Retroviridae and infections of retroviruses (visna-maedi; enzootik bovine leukosis, caprine arthritis encephalitis, feline leukosis and equine infectious anemia viruses)

Week 12 - Preparation Work

Immunofluorescence test and ELISA

Week 13 - Theoretical

Transmissible spongioform encephalopathies

Week 13 - Preparation Work

Molecular techniques using in Virology. Polimerase chain Reaction.

Week 14 - Theoretical

Retroviridae and infections of adenoviruses,Herpesviridae familyası ve oluşturduğu enfeksiyonlar (IBR/IPV, Bovine mamilitis, Coryza, atların herpesvirus enfeksiyonu)

Week 14 - Preparation Work

Papovaviridae ve Parvoviridae and their infections (canine oral papillomatosis, papillomatosis in cattle, sheep and caprine)

Assessment Methods and Criteria

Type of Assessment	Count	Percent
Midterm Examination	1	%40
Final Examination	1	%60

Workload Calculation

Activities	Count	Preparation	Time	Total Work Load (hours)
Lecture - Theory	14	0	5	70
Midterm Examination	1	10	1	11
Final Examination	1	18	1	19
TOTAL WORKLOAD (hours)				100

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