Information Package / Course Catalogue - Adnan Menderes University

General Information Unit Staff Academic Information Programme Outcomes Course Structure Diagram Contact Information

Person Responsible for Information Package

Fundamentals of Toxicology

Course Code	: BYL400
Course Type	: Area Elective
Couse Group	: First Cycle (Bachelor's Degree)
Education Language	: Turkish
Work Placement	: N/A

Theory	: 2
Prt.	: 0
Credit	: 2
Lab	: 0
ECTS	: 4

Objectives of the Course

The aim of this course is to provide comprehensive information about the basic concepts of Toxicology and general mechanisms of toxicity.

Course Content

Introduction of toxicology science, its history, subjects and fields of study. Classification of toxic agents, exposure to toxic agents, dose-response relationship, general mechanisms of toxicity, biotransformation of toxic substances, toxicity and detoxification.

Name of Lecturer(s)

Assoc. Prof. Özlem Sultan ASLANTÜRK

Learning Outcomes

1.	Knows and defines the basic concepts related to toxicology.
2.	Classify toxic agents and know the forms of exposure to toxic agents.
3.	Knows and explains the general mechanisms of toxicity.
4.	Learn and explain the damages caused by toxic agents in living systems and the basic mechanisms that cause these damages.
5.	Knows and explains the biotransformation mechanisms of toxic agents.
6.	Be able to evaluate the basic principles of toxicity tests.
7.	Gains knowledge of exposure to toxic agents, types of toxic effects, dose-response relationship.
8.	Gains the ability to evaluate studies related to toxicology in the fields of pharmaceutical industry, forensic medicine, environmental management and academic research.

Recommended or Required Reading

1.	Introduction to Toxicology.Timbrell, J. 2002. 3rd Edition, Taylor and Francis Publishing. ISBN 0-415-247-632
2.	Toksikoloji. Vural, N. 1996. Ankara Üniversitesi Yayınevi, Ankara.

Weekly Detailed Course Contents

Week 1 - Theoretical

Introduction to the science of toxicology: Its history, basic concepts, subjects and fields of study

Week 2 - Theoretical

Classification of toxic agents, spectrum of toxic dose

Week 3 - Theoretical

Patterns of exposure to toxic agents, absorption, distribution, release and metabolism

Week 4 - Theoretical

Dose-response relationship and determination of lethal dose

Week 5 - Theoretical

General mechanisms of toxicity

Week 6 - Theoretical

Toxic agents and xenobiotics

Week 7 - Theoretical

Toxic effects of some metals and other inorganic contaminants

Week 8 - Theoretical

Organic pollutants and their toxic effects (Midterm exam)

Week 9 - Theoretical

Environmental toxicity

Week 10 - Theoretical

Reproductive and developmental toxicity

Week 11 - Theoretical

Genetic toxicology

Week 12 - Theoretical

Food and drug toxicity

Week 13 - Theoretical

Biotransformation of toxic substances

Week 14 - Theoretical

Cellular distribution, toxicity and detoxification in biotransformation.

Assessment Methods and Criteria

Type of Assessment	Count	Percent
Midterm Examination	1	%40
Final Examination	1	%60

Workload Calculation

Activities	Count	Preparation	Time	Total Work Load (hours)
Lecture - Theory	14	3	2	70
Midterm Examination	1	10	1	11
Final Examination	1	12	1	13
TOTAL WORKLOAD (hours)				94

Contribution of Learning Outcomes to Programme Outcomes

	PÇ-1	PÇ-2	PÇ-3	PÇ-4	PÇ-5	PÇ-6	PÇ-7	PÇ-8	PÇ-9	PÇ-10	PÇ-11	PÇ-12	PÇ-13
OÇ-1	3		4							3			3
OÇ-2	4		3		4			4		4			3
OÇ-3			4				3	4		4			4
OÇ-4			5					3		4			3
OÇ-5			5					3		4			3
OÇ-6
OÇ-7
OÇ-8

Person Responsible for Information Package