Information Package / Course Catalogue
Cell Differentiation and Its Methods
Course Code: KHÜ524
Course Type: Area Elective
Couse Group: Second Cycle (Master's Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 2
Prt.: 0
Credit: 2
Lab: 0
ECTS: 6
Objectives of the Course

The aim of this course is to give information about differentiation methods and their clinical usage from stem cells to various cells.

Course Content

The concept of differentiation in stem cells, direct differentiation, differentiation from stem cells to various cells and their potential use in clinical will be explained.

Name of Lecturer(s)
Learning Outcomes
1.Examine differentiation methods and materials used from stem cells to other cells.
2.Learn differentiation types
3.Discuss the potential of differentiating cells in clinical use
4.Have information about differentiation from mesenchymal stem cells
5.Have knowledge about differentiation from pluripotent stem cells
Recommended or Required Reading
1.Sell S, Stem Cells Handbook, Humana Press, second edition, 2013
2.Alberio R, Epiblast Stem Cells, Humana Press, Methods and protocols,Wiley Blackwell, 2013
3.Regad T, Sayers TJ, Rees R, Principle of Stem Cell Biology and Cancer,
4.Healy L, Ruban L, Atlas of Human Pluripotent Stem Cells in Culture, Springer, 2015
5.Rich IN, Stem Cell Protocols, Humana Press, 2015
Weekly Detailed Course Contents
Week 1 - Theoretical
The concept of differentiation in stem cells
Week 2 - Theoretical
Small molecules used in differentiation
Week 3 - Theoretical
Direct differentiation
Week 4 - Theoretical
Differentiation from mesenchymal stem cells
Week 5 - Theoretical
Differentiation from pluripotent stem cells-I
Week 6 - Theoretical
Differentiation from pluripotent stem cells-II
Week 7 - Theoretical
Differentiation from stem cells to retinal cells
Week 8 - Intermediate Exam
Mid-term exam
Week 9 - Theoretical
Differentiation from stem cells to heart cells
Week 10 - Theoretical
Differentiation from stem cells to nerve cells
Week 11 - Theoretical
Clinical use of differentiated cells-I
Week 12 - Theoretical
Clinical use of differentiated cells-II
Week 13 - Theoretical
Review of articles and discussion-I
Week 14 - Theoretical
Review of articles and discussion-II
Week 15 - Final Exam
Final exam
Assessment Methods and Criteria
Type of AssessmentCountPercent
Midterm Examination1%20
Final Examination1%60
Assignment1%20
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory131239
Assignment218138
Midterm Examination124226
Final Examination148250
TOTAL WORKLOAD (hours)153
Contribution of Learning Outcomes to Programme Outcomes
PÇ-1
PÇ-2
PÇ-3
PÇ-4
PÇ-5
PÇ-6
PÇ-7
PÇ-8
PÇ-9
PÇ-10
OÇ-1
2
2
OÇ-2
2
2
2
OÇ-3
3
4
OÇ-4
2
2
2
OÇ-5
2
2
2
Adnan Menderes University - Information Package / Course Catalogue