Information Package / Course Catalogue
Relations Between Cells and Micro Environment
Course Code: KHÜ525
Course Type: Area Elective
Couse Group: Second Cycle (Master's Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 2
Prt.: 0
Credit: 2
Lab: 0
ECTS: 6
Objectives of the Course

Information will be given about the relationships between the stem cells and the place-organ.

Course Content

Side face connections, cancer initiator cell, niche concept in stem cell, extracellular matrix, microenvironment of the stem cell and its relationship with the cells will be examined.

Name of Lecturer(s)
Learning Outcomes
1.Examine the intercellular relationship in stem cells
2.Discuss the concept of niche in stem cells
3.Have knowledge about microenvironment relations in stem cells
4.Have knowledge about the concept of circulating cells
5.Have an idea about the inverse Warburg effect
Recommended or Required Reading
1.Sell S, Stem Cells Handbook, Humana Press, second edition, 2013
2.Alberio R, Epiblast Stem Cells, Humana Press, Methods and protocols,Wiley Blackwell, 2013
3.Regad T, Sayers TJ, Rees R, Principle of Stem Cell Biology and Cancer,
4.Healy L, Ruban L, Atlas of Human Pluripotent Stem Cells in Culture, Springer, 2015
5.Rich IN, Stem Cell Protocols, Humana Press, 2015
Weekly Detailed Course Contents
Week 1 - Theoretical
Course description and introduction
Week 2 - Theoretical
Side face connections
Week 3 - Theoretical
Communication mechanisms in the cell
Week 4 - Theoretical
Contact inhibition
Week 5 - Theoretical
The concept of niche in stem cells
Week 6 - Theoretical
Cancer initiator cell
Week 7 - Theoretical
Circulating cancer cell concept
Week 8 - Intermediate Exam
Mid-term exam
Week 9 - Theoretical
The concept of niche in cancer
Week 10 - Theoretical
Microenvironment and fibroblasts
Week 11 - Theoretical
Microenvironment and immune cells
Week 12 - Theoretical
Cellular stress
Week 13 - Theoretical
Extracellular matrix
Week 14 - Theoretical
Reverse Warburg effect
Week 15 - Final Exam
Final exam
Assessment Methods and Criteria
Type of AssessmentCountPercent
Midterm Examination1%20
Final Examination1%60
Assignment1%20
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory131239
Assignment218138
Midterm Examination124226
Final Examination148250
TOTAL WORKLOAD (hours)153
Contribution of Learning Outcomes to Programme Outcomes
PÇ-1
PÇ-2
PÇ-3
PÇ-4
PÇ-5
PÇ-6
PÇ-7
PÇ-8
PÇ-9
PÇ-10
OÇ-1
2
2
2
OÇ-2
2
2
3
OÇ-3
3
2
3
OÇ-4
3
2
3
OÇ-5
3
2
3
Adnan Menderes University - Information Package / Course Catalogue