Information Package / Course Catalogue
Neural Stem Cells and Experimental Animal Models
Course Code: KHÜ528
Course Type: Area Elective
Couse Group: Second Cycle (Master's Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 2
Prt.: 0
Credit: 2
Lab: 0
ECTS: 6
Objectives of the Course

The aim of this course is to give information about neural stem cell and experimental animal models and their clinical use potential.

Course Content

Neural stem cells in embryogenesis, signal molecules in neurogenesis, neural stem cell production, neural stem cell characterization, cell culture media properties for neural stem cell, IPS and neural differentiation, neural stem cell and clinical applications, cancer stem cell in brain, neurodegeneration model, dementia model and trauma-injury model.

Name of Lecturer(s)
Learning Outcomes
1.Learns neural cell sources and characterization
2.Have knowledge about neural stem cell culture
3.Have knowledge about experimental animal neural disease models
4.Discuss the clinical use of neural stem cells
5.Have an idea about neurodegeneration models
Recommended or Required Reading
1.Sell S, Stem Cells Handbook, Humana Press, second edition, 2013
2.Alberio R, Epiblast Stem Cells, Humana Press, Methods and protocols,Wiley Blackwell, 2013
3.Regad T, Sayers TJ, Rees R, Principle of Stem Cell Biology and Cancer,
4.Healy L, Ruban L, Atlas of Human Pluripotent Stem Cells in Culture, Springer, 2015
5.Rich IN, Stem Cell Protocols, Humana Press, 2015
Weekly Detailed Course Contents
Week 1 - Theoretical
Course description and introduction
Week 2 - Theoretical
Development of nervous system
Week 3 - Theoretical
Neural stem cells in embryogenesis
Week 4 - Theoretical
Signal molecules in neurogenesis
Week 5 - Theoretical
Isolation of neural stem cells
Week 6 - Theoretical
Neural stem cell characterization
Week 7 - Theoretical
Cell culture media properties for neural stem cells
Week 8 - Intermediate Exam
Mid-term exam
Week 9 - Theoretical
IPS and neural differentiation
Week 10 - Theoretical
Neural stem cells and clinical applications
Week 11 - Theoretical
Cancer stem cell in brain
Week 12 - Theoretical
Neurodegeneration model
Week 13 - Theoretical
Dementia model
Week 14 - Theoretical
Trauma-Damage model
Week 15 - Final Exam
Final exam
Assessment Methods and Criteria
Type of AssessmentCountPercent
Midterm Examination1%20
Final Examination1%60
Assignment1%20
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory131239
Assignment218138
Midterm Examination124226
Final Examination148250
TOTAL WORKLOAD (hours)153
Contribution of Learning Outcomes to Programme Outcomes
PÇ-1
PÇ-2
PÇ-3
PÇ-4
PÇ-5
PÇ-6
PÇ-7
PÇ-8
PÇ-9
PÇ-10
OÇ-1
1
5
3
3
1
3
OÇ-2
1
3
2
2
3
1
3
3
3
OÇ-3
2
2
2
4
3
2
OÇ-4
2
2
2
2
2
3
4
OÇ-5
2
2
2
4
3
2
Adnan Menderes University - Information Package / Course Catalogue