Information Package / Course Catalogue
Molecular Essentials of Stem Cell Structure
Course Code: KHÜ501
Course Type: Required
Couse Group: Second Cycle (Master's Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 2
Prt.: 2
Credit: 3
Lab: 0
ECTS: 7
Objectives of the Course

The aim of this course is to explain the basic properties, molecular and genetic properties of stem cells and their surface structures.

Course Content

Pluripotence, self-renewal and differentiation, stem cell niche, stem cell-related genetic and epigenetic properties, stem cell-specific markers and stem cell types will be explained.

Name of Lecturer(s)
Prof. Kemal ERGİN
Learning Outcomes
1.Explain the basic features of stem cell structure.
2.Explain the genetic and epigenetic properties of stem cells.
3.Knows the stem cell markers.
4.Distinguishes stem cell types.
5.Gains knowledge of stem cell signaling.
Recommended or Required Reading
1.Sell S, Stem Cells Handbook, Humana Press, second edition, 2013.
2.Alberio R, Epiblast Stem Cells, Humana Press, Methods and protocols,Wiley Blackwell, 2013
3.Regad T, Sayers TJ, Rees R, Principle of Stem Cell Biology and Cancer,
4.Healy L, Ruban L, Atlas of Human Pluripotent Stem Cells in Culture, Springer, 2015
5.Rich IN, Stem Cell Protocols, Humana Press, 2015
6.R. Lanza, J. Gearhart, B. Hogan, D. Melton, R. Pederson, E.D. Thomas, J.Thomson, I. Wilmut. Essentials of Stem Cell Biology. Academic Press.
7.Lewandowski M, Mouse Molecular Embryology, Methods and Protocols, Humana Press, 2014.
Weekly Detailed Course Contents
Week 1 - Theoretical
Course description and general information
Week 2 - Theoretical
Basic features of stem cells-I: pluripotency and self-renewal
Week 3 - Theoretical
Basic features of stem cells-II: differentiation
Week 4 - Theoretical
Stem cell life cycle and aging
Week 5 - Theoretical
Stem cell niche
Week 6 - Theoretical
Genes and genome structure in stem cells
Week 7 - Theoretical
Epigenetic mechanisms in stem cells
Week 8 - Intermediate Exam
Mid-term exam
Week 9 - Theoretical
Stem cell and signaling
Week 10 - Theoretical
Pluripotent stem cells and markers
Week 11 - Theoretical
Mesenchymal stem cells and markers
Week 12 - Theoretical
Fetal and adult stem cells
Week 13 - Theoretical
Bone marrow and cord blood stem cells
Week 14 - Theoretical
Cancer stem cell
Week 15 - Final Exam
Final exam
Assessment Methods and Criteria
Type of AssessmentCountPercent
Midterm Examination1%40
Final Examination1%60
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory131352
Assignment410248
Midterm Examination124226
Final Examination148250
TOTAL WORKLOAD (hours)176
Contribution of Learning Outcomes to Programme Outcomes
PÇ-1
PÇ-2
PÇ-3
PÇ-4
PÇ-5
PÇ-6
PÇ-7
PÇ-8
PÇ-9
PÇ-10
OÇ-1
5
4
3
4
3
OÇ-2
3
4
5
3
3
OÇ-3
4
5
5
3
2
OÇ-4
4
5
3
3
2
OÇ-5
4
5
3
3
2
Adnan Menderes University - Information Package / Course Catalogue