Information Package / Course Catalogue
Free Radicals and Antioxidant Systems
Course Code: BDY528
Course Type: Area Elective
Couse Group: Second Cycle (Master's Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 2
Prt.: 2
Credit: 3
Lab: 0
ECTS: 5
Objectives of the Course

Examining oxidative tissue damage caused by free radicals, the roles of various pathologies and antioxidant defense systems.

Course Content

Information about identification of the free radicals by making, types, resources and effects on biological systems, also the mechanisms to eliminate the harmful effects of them will be given in this course.

Name of Lecturer(s)
Prof. Serdal ÖĞÜT
Learning Outcomes
1.Knows exogenous antioxidants.
2.Knows the natural antioxidants.
3.Knows the mechanisms of antioxidants.
4.Knows the reactions of free radicals with molecules in the organism.
5.Defines free radicals, knows diseases that cause of them.
Recommended or Required Reading
1.basics of toxicology, Lange yayınları
Weekly Detailed Course Contents
Week 1 - Theoretical
Definition and formation of free radicals
Week 2 - Theoretical
Free oxygen radicals and reactive oxygen species
Week 3 - Theoretical
Intracellular and biological resources of free radicals
Week 4 - Theoretical
Transition metals and free radical formation
Week 5 - Theoretical
Phagocytosis and respiratory burst
Week 6 - Theoretical
effect of antioxidant
Week 7 - Theoretical
efeect of oxidant
Week 8 - Theoretical
Effects of free radicals in membrane lipids (midterm exam)
Week 9 - Theoretical
Effects of free radicals in proteins
Week 10 - Theoretical
Effects of free radicals in nucleic acids
Week 11 - Theoretical
Effects of free radicals in carbohydrates
Week 12 - Theoretical
Oxidative damage mechanisms
Week 13 - Theoretical
Endogenous and Exogenous Antioxidants
Week 14 - Theoretical
Antioxidant effects of melatonin, resveratrol and alpha-lipoic acid
Assessment Methods and Criteria
Type of AssessmentCountPercent
Midterm Examination1%15
Final Examination1%70
Assignment5%15
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory141242
Individual Work115419
Midterm Examination120222
Final Examination140242
TOTAL WORKLOAD (hours)125
Contribution of Learning Outcomes to Programme Outcomes
PÇ-1
PÇ-2
PÇ-3
PÇ-4
PÇ-5
OÇ-1
4
3
3
3
4
OÇ-2
3
3
3
3
3
OÇ-3
4
4
3
4
4
OÇ-4
4
3
4
4
3
OÇ-5
4
3
3
3
3
Adnan Menderes University - Information Package / Course Catalogue
2026