Information Package / Course Catalogue
Eukaryotic Gene Expression
Course Code: ZBY518
Course Type: Area Elective
Couse Group: Second Cycle (Master's Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 3
Prt.: 0
Credit: 3
Lab: 0
ECTS: 8
Objectives of the Course

The objective of this course is to provide an overview of the structure of the eukaryotic genome, gene expression and molecular control mechanisms.

Course Content

In this course, it is told about the structure of eukaryotic genome and the molecular processes of gene expression, various molecular mechanisms that regulate gene expression in an eukaryotic cell, gene expression and control mechanisms in prokaryotic and eukaryotic organisms and regulation of gene expression during development.

Name of Lecturer(s)
Lec. Murat Kemal AVCI
Learning Outcomes
1.Explain the structure of eukaryotic genome and identify the molecular processes of gene expression.
2.Discuss various molecular mechanisms that regulate gene expression in an eukaryotic cell.
3.Compare gene expression and control mechanisms in prokaryotic and eukaryotic organisms.
4.Define regulation of gene expression during development.
5.Gene regulation mechanism is learned
Recommended or Required Reading
1.Molecular Biology of the Gene. Watson, J.D. et al. 6th ed. 2007. Benjamin Cummings
2.Lewin’s Genes X. Krebs, J.E. et al. 10th ed. 2009. Jones and Bartlett Publishers
3.Molecular Biology of the Cell. Alberts, B. et al. 5th ed. 2007. Garland Science
4.Molecular Cell Biology. Lodish, H. et al. 6th ed. 2007. W.H. Freeman and Company
Weekly Detailed Course Contents
Week 1 - Theoretical
Eukaryotic cell and genome structure from yeast to higher organisms
Week 2 - Theoretical
RNA genes, RNA polymerases
Week 3 - Theoretical
Transcriptional control mechanisms
Week 4 - Theoretical
Nucleosomes and transcription
Week 5 - Theoretical
Genetic recombination, repeating sequences, gene amplification
Week 6 - Theoretical
Gene clusters, gene families, transposons
Week 7 - Theoretical
Translation: components and mechanisms
Week 8 - Theoretical
RNA splicing, Introns and exons
Week 9 - Theoretical
Regulation mechanisms of gene expression
Week 10 - Theoretical
Proteins and targeted protein cleavage
Week 11 - Theoretical
Gene expression according to growth phase and tissue
Week 12 - Theoretical
Gene expression according to growth phase and tissue
Week 13 - Theoretical
Regulatory networks and signal transduction pathways
Week 14 - Theoretical
Relationships between eukaryotic and prokaryotic gene expressions
Assessment Methods and Criteria
Type of AssessmentCountPercent
Midterm Examination1%30
Final Examination1%70
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory14103182
Midterm Examination1819
Final Examination1819
TOTAL WORKLOAD (hours)200
Contribution of Learning Outcomes to Programme Outcomes
PÇ-1
PÇ-2
PÇ-3
PÇ-4
PÇ-5
OÇ-1
3
4
5
4
4
OÇ-2
5
5
5
3
5
OÇ-3
5
5
5
3
4
OÇ-4
5
5
5
3
5
OÇ-5
4
4
5
5
5
Adnan Menderes University - Information Package / Course Catalogue
2026