Information Package / Course Catalogue
| Course Code | : ZBY536 |
| Course Type | : Area Elective |
| Couse Group | : Second Cycle (Master's Degree) |
| Education Language | : Turkish |
| Work Placement | : N/A |
| Theory | : 3 |
| Prt. | : 0 |
| Credit | : 3 |
| Lab | : 0 |
| ECTS | : 8 |
It is aimed to identify gene function changes that cannot be explained by changes in DNA sequence and to discuss the mechanisms involved in detail.
Definition of epigenetics, gene circuit elements and basics of gene control Chromatin and chromosome architecture, Epigenetic mechanisms, Histone modifications and epigenetic gene regulation, DNA-level epigenetic modifications, Basic functions of non-coding RNAs and RNA epigenetics, Genomic imprinting, Epigenetic analysis methods
| Lec. Evrim ELÇİN |
| 1. | Will be able to explain the concept of epigenetics and its multi-layered mechanisms |
| 2. | Will be able to discuss epigenetic mechanisms through specific examples |
| 3. | To have knowledge on DNA methylation, histone modifications and epigenetic mechanisms of gene regulation |
| 4. | To have knowledge about genomic imprinting and epigenetic analysis method |
| 5. | Will be able to explain the concept of epigenetics and its multi-layered mechanisms |
| 1. | Epigenetics, Cold Spring Harbor Laboratory Press, 2015 |
| 2. | Handbook of Epigenetics: The New Molecular and Medical Genetics, 2023, Edited by: Trygve Tollefsbol, Academic Press. |
| 3. | Lewin’s Genes XII, 2018, Jones & Bartlett Learning, LLC |
| Type of Assessment | Count | Percent |
|---|---|---|
| Midterm Examination | 1 | %30 |
| Final Examination | 1 | %70 |
| Activities | Count | Preparation | Time | Total Work Load (hours) |
|---|---|---|---|---|
| Lecture - Theory | 14 | 11 | 2 | 182 |
| Midterm Examination | 1 | 8 | 1 | 9 |
| Final Examination | 1 | 8 | 1 | 9 |
| TOTAL WORKLOAD (hours) | 200 | |||
PÇ-1 | PÇ-2 | PÇ-3 | PÇ-4 | PÇ-5 | |
OÇ-1 | 5 | 5 | 5 | 5 | 5 |
OÇ-2 | 5 | 5 | 5 | 5 | 4 |
OÇ-3 | 5 | 5 | 5 | 5 | 4 |
OÇ-4 | 5 | 4 | 4 | 5 | 4 |
OÇ-5 | 5 | 3 | 3 | 3 | 3 |