Pharmacokinetics moddeleme, kinetic parameters and factors affecting them with the WinNonlin software program utilized in the calculation of these parameters provide information.

Behavior of drugs in the body (absorption, distribution, metabolism, and excretion), pharmacokinetic modeling, pharmacokinetic parameters (AUC, Tmax, T1 / 2, OKS, Cl, Vd), the factors that lead to changes in these parameters (age, species, race, disease, genetic , the environment, etc.). drug efficacy and the effects of measures to be taken in this case and the WinNonlin pharmacokinetic software package