
| Course Code | : BİO655 |
| Course Type | : Area Elective |
| Couse Group | : Third Cycle (Doctorate Degree) |
| Education Language | : Turkish |
| Work Placement | : N/A |
| Theory | : 3 |
| Prt. | : 0 |
| Credit | : 3 |
| Lab | : 0 |
| ECTS | : 8 |
This course aims to explain how genetic variations influence biological responses to dietary components and to provide advanced knowledge on the interactions between nutrition, genomics, and epigenetics. Students are expected to develop the ability to scientifically evaluate personalized nutrition approaches based on individual genetic profiles, interpret nutrigenetic and nutrigenomic data, analyze gene–diet interactions at the molecular level, and apply this knowledge to health promotion and disease management. Additionally, the course aims to foster a multidisciplinary perspective by addressing the ethical, societal, and clinical implications of nutrigenomic data.
This course focuses on nutrigenetics and nutrigenomics, which examine how individuals’ genetic makeup influences their responses to dietary components and the effects of nutrition on gene expression. It covers nutrition–genome interactions at the levels of the genome, epigenome, transcriptome, and metabolome, as well as the scientific basis of personalized nutrition strategies and their applications in public health. The course also discusses the impact of gene–diet interactions on chronic diseases such as obesity, diabetes, cardiovascular diseases, and cancer. Students will gain advanced knowledge and analytical skills related to nutrition-sensitive genetic variations, analysis of nutrigenetic biomarkers, epigenetic mechanisms, and individualized medical nutrition approaches.
| Assoc. Prof. Tülay ÇELİK |
| 1. | Defines the concepts of nutrigenomics and nutrigenetics, and explains the differences between them. |
| 2. | Analyzes the effects of nutrients on gene expression and epigenetic mechanisms. |
| 3. | Evaluates the relationship between genetic polymorphisms and individual dietary responses. |
| 4. | Interprets gene-diet interactions in common diseases such as obesity, diabetes, cardiovascular diseases, and cancer. |
| 5. | Discusses the applicability and limitations of nutrigenetic testing from a scientific perspective. |
| 6. | Explains the tripartite relationship between microbiota, genetic makeup, and nutrition. |
| 7. | Assesses the scientific basis and potential health impacts of personalized nutrition approaches. |
| 8. | Analyzes the ethical, social, and legal aspects of nutrigenomic applications. |
| 1. | Carlberg C, Ulven AM, Molnar F. 2019. Nutrigenomik. Çeviri Editörleri: Yılmaz, S., Uçar A. Pelikan Kitabevi. ISBN: 9786052268919 |
| 2. | Bş, M., Karaca E. 2023. Nutrigenetik Kişisel Beslenme Bilimini Uygulamak. Akademisyen Yayınevi |
| 3. | Temizkan, G. 2021. Genetik: Temel İlke ve Kavramlar. Ankara Nobel Tıp Kitabevi. ISBN: 9786257564045. - |
| 4. | Ordovas JM. 2004. Nutrigenetics And Nutrigenomics, World Review of Nutrition and Dietetics,Vol.93,Karger, 2004 |
| Type of Assessment | Count | Percent |
|---|---|---|
| Midterm Examination | 1 | %30 |
| Final Examination | 1 | %70 |
| Activities | Count | Preparation | Time | Total Work Load (hours) |
|---|---|---|---|---|
| Lecture - Theory | 14 | 2 | 3 | 70 |
| Assignment | 2 | 10 | 2 | 24 |
| Reading | 12 | 3 | 0 | 36 |
| Individual Work | 10 | 4 | 0 | 40 |
| Midterm Examination | 1 | 10 | 2 | 12 |
| Final Examination | 1 | 20 | 2 | 22 |
| TOTAL WORKLOAD (hours) | 204 | |||
PÇ-1 | PÇ-2 | PÇ-3 | PÇ-4 | PÇ-5 | PÇ-6 | PÇ-7 | PÇ-8 | PÇ-9 | PÇ-10 | PÇ-11 | PÇ-12 | PÇ-13 | PÇ-14 | |
OÇ-1 | 5 | 4 | 3 | 2 | 4 | 3 | 3 | 4 | 4 | 3 | ||||
OÇ-2 | 4 | 5 | 4 | 3 | 4 | 3 | 3 | 4 | 3 | 4 | ||||
OÇ-3 | 5 | 5 | 4 | 2 | 4 | 3 | 3 | 4 | 4 | 3 | ||||
OÇ-4 | 5 | 5 | 4 | 3 | 4 | 4 | 3 | 5 | 5 | 4 | ||||
OÇ-5 | 4 | 5 | 4 | 2 | 4 | 4 | 3 | 4 | 4 | 3 | ||||
OÇ-6 | 4 | 3 | 3 | 3 | 3 | 3 | 2 | 2 | 4 | 4 | ||||
OÇ-7 | 3 | 3 | 3 | 2 | 3 | 2 | 2 | 3 | 3 | 2 | ||||
OÇ-8 | 3 | 3 | 3 | 2 | 3 | 3 | 3 | 4 | 4 | 2 | ||||