Information Package / Course Catalogue
Microbial Protein Toxins
Course Code: MBTK637
Course Type: Area Elective
Couse Group: Third Cycle (Doctorate Degree)
Education Language: English
Work Placement: N/A
Theory: 3
Prt.: 0
Credit: 3
Lab: 0
ECTS: 10
Objectives of the Course

The aim of this course is to give information about microbial protein toxins

Course Content

Toxins produced by microorganisms, their classification, structures, genetic properties and regulation of their expression, physiologic and pathologic effects of toxins

Name of Lecturer(s)
Prof. Gamze BAŞBÜLBÜL
Learning Outcomes
1.To have current information about microbial proteins toxins
2.Will know mechanisms of microbial toxins
3.Will have current knowledge about toxins synthesed by microorganisms and their relation with pathologies
4.Will know recombinant microbial toxins
5. Will know genetic properties of microbial toxins, their expression and regulation
Recommended or Required Reading
1.Introduction to Clinical Microbiology ISBN-13 ? 978-6205436967
2.Microbial Protein Toxins ISBN 978-3-540-23562-0
Weekly Detailed Course Contents
Week 1 - Theoretical
Introduction to toxins
Week 2 - Theoretical
Genetic properties of microbial toxins
Week 3 - Theoretical
Neurotoxins
Week 4 - Theoretical
Enterotoxins
Week 5 - Theoretical
Cytotoxins
Week 6 - Theoretical
Recombinant microbial toxins and their use
Week 7 - Theoretical
Cholera toxin and mechanism of action
Week 8 - Theoretical
Anthrax toxin and mechanism of action (Midterm exam)
Week 9 - Theoretical
Diphtheria toxin amd mechanism of action
Week 10 - Theoretical
Botilinum toxin and mechanism of action
Week 11 - Theoretical
Aflatoxin and mechanism of action
Week 12 - Theoretical
Tetanous toxin and mechanism of action
Week 13 - Theoretical
Shigella dysenteria toxin and mechanism of action
Week 14 - Theoretical
Bordetelle pertusis toxin and mechanism of action
Assessment Methods and Criteria
Type of AssessmentCountPercent
Midterm Examination1%30
Final Examination1%70
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory140342
Assignment501575
Term Project50840
Laboratory50420
Individual Work130452
Quiz60318
Midterm Examination1033
Final Examination1033
TOTAL WORKLOAD (hours)253
Contribution of Learning Outcomes to Programme Outcomes
PÇ-1
PÇ-2
PÇ-3
PÇ-4
PÇ-5
PÇ-6
PÇ-7
PÇ-8
PÇ-9
PÇ-10
PÇ-11
PÇ-12
PÇ-13
OÇ-1
5
5
3
5
5
3
4
4
4
4
3
3
5
OÇ-2
5
5
3
5
5
3
4
4
4
4
3
3
5
OÇ-3
5
5
3
4
4
3
5
5
5
5
3
3
5
OÇ-4
5
5
3
4
4
3
5
5
5
5
3
3
5
OÇ-5
5
5
3
4
4
3
5
5
5
5
3
3
5
Adnan Menderes University - Information Package / Course Catalogue
2026