Information Package / Course Catalogue
Advanced Studies on Cell Death in Cancer
Course Code: ONK604
Course Type: Required
Couse Group: Third Cycle (Doctorate Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 2
Prt.: 2
Credit: 3
Lab: 0
ECTS: 8
Objectives of the Course

To explain the relationship between cell death types and cancer. To provide differentiation between programmed and unscheduled cell death types.

Course Content

Subjects such as Necrotic Cell death, Apoptosis formation mechanisms, Autophagy Mechanisms and Autophagy-related Signaling pathways, Other Programmed Cell Death Types (Piroptosis, Necroptosis, Partanatosis, Ferroptosis) and Cancer will be covered.

Name of Lecturer(s)
Prof. Kemal ERGİN
Learning Outcomes
1.Knows necrotic cell death.
2.Examines the mechanisms and regulation of apoptosis and autophagy.
3.Knows the methods of analyzing apoptosis and autophagy.
4.Knows the place of apoptosis and autophagy in cancer treatments.
5.Understands the roles of piroptosis, necroptosis, partanatosis and ferroptosis in cancer.
6.Discusses the differences of necrosis from other cell death types.
Recommended or Required Reading
1.Diagnostic Approach to Clinical Oncology Mario W. Fiorentino PICCIN 1999
2.Cancer Principles and Practice of Oncology Devita VT, Lawrence TS, Rosenberg SA, Wolters Kluwer& Lippincott Willams & Wilkins 2008 Eighth Edition.
Weekly Detailed Course Contents
Week 1 - Theoretical & Practice
Cell Death Overview
Week 2 - Theoretical & Practice
Necrotic Cell Death
Week 3 - Theoretical & Practice
Signal Pathways Leading to Cell Death
Week 4 - Theoretical & Practice
Apoptosis formation mechanisms
Week 5 - Theoretical & Practice
Regulation of Apoptosis
Week 6 - Theoretical & Practice
Apoptosis Analysis Methods
Week 7 - Theoretical & Practice
Cancer Treatments and Apoptosis-1
Week 8 - Theoretical & Practice
Cancer Treatments and Apoptosis-2 (Midterm)
Week 9 - Theoretical & Practice
Autophagy Mechanisms and Autophagy-related Signal Pathways
Week 10 - Theoretical & Practice
Regulation of Autophagy
Week 11 - Theoretical & Practice
Autophagy Analysis Methods
Week 12 - Theoretical & Practice
Cancer Treatments and Autophagy
Week 13 - Theoretical & Practice
Other Programmed Cell Death Types (Piroptosis, Necroptosis, Partanatosis, Ferroptosis) and Cancer
Week 14 - Theoretical & Practice
Unprogrammed Cell Death Types (Necrosis) and Cancer
Week 15 - Final Exam
Final
Assessment Methods and Criteria
Type of AssessmentCountPercent
Midterm Examination1%40
Final Examination1%60
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory131239
Lecture - Practice131239
Assignment224048
Midterm Examination124226
Final Examination148250
TOTAL WORKLOAD (hours)202
Contribution of Learning Outcomes to Programme Outcomes
PÇ-1
PÇ-2
PÇ-3
PÇ-4
PÇ-5
PÇ-6
PÇ-7
PÇ-8
PÇ-9
PÇ-10
PÇ-11
PÇ-12
PÇ-13
PÇ-14
PÇ-15
OÇ-1
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
OÇ-2
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
OÇ-3
4
4
4
4
4
5
4
4
4
5
5
5
5
5
5
OÇ-4
5
5
4
4
5
5
5
5
5
5
5
4
5
5
5
OÇ-5
4
4
4
4
5
5
5
5
4
5
4
5
4
4
4
OÇ-6
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
Adnan Menderes University - Information Package / Course Catalogue
2026