To define basic oncology concepts, to understand the molecular basis of carcinogenesis and anticancer therapy with examples.

The aim of this course is to understand the relationship between carcinogenesis, cell cycle and cancer, differentiation, its role in transformation and cancer development and its molecular mechanisms. Cell death mechanisms, angiogenesis, invasion and metastasis, signal pathways in cancer, the importance of oncogene and tumor suppressor genes in cancer diagnosis, treatment and follow-up. In practice courses, cancer cell culture, Western Blot application, DNA from tumor tissue, RNA isolation, and real time PCR mutation analysis in cancer diagnosis will be discussed.