Information Package / Course Catalogue
Cell and Gene Treatments in Oncology
Course Code: ONK627
Course Type: Area Elective
Couse Group: Third Cycle (Doctorate Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 2
Prt.: 2
Credit: 3
Lab: 0
ECTS: 8
Objectives of the Course

The aim of this course is to comprehend the biological, molecular and genetic features of the mechanisms of cellular and gene therapies in relation to the clinical parameters with translation. Thus, gaining basic information about cellular and gene therapy techniques and applications, which are among the newly developed treatment approaches in cancer researches, to introduce the necessary tools and laboratory methods for cell and gene treatments, and thus continue thesis and research projects involving cell and gene treatments.

Course Content

Topics such as gene transfer methods, genetic modification of immune response, anti-tumor effect genes and cancer modulation, gene therapy vectors will be covered.

Name of Lecturer(s)
Prof. Gökay BOZKURT
Learning Outcomes
1.Can express cellular and gene treatments in cancer.
2.Recognizes and comprehends cellular and gene therapy methods in cancer.
3.Recognize and comprehend cellular and gene therapy types in cancer
4.To be able to identify and interpret cellular and gene treatments in cancer
5.To be able to research and inquire about cellular and gene treatments in cancer
Recommended or Required Reading
1.Cancer Principles and. Practice of Oncology 8.th. Edition (Vincent Devita, Samuel Hellamas),
2.LEVIN’S GENES X, Jocelyn E. Krebs, Elliott S. Goldstein, Stephen T. Kilpatrick , Jones and Bartlett 2011
Weekly Detailed Course Contents
Week 1 - Theoretical & Practice
Introduction to cellular and gene therapies
Week 2 - Theoretical & Practice
Gene transfer methods
Week 3 - Theoretical & Practice
Gene marking studies
Week 4 - Theoretical & Practice
Genetic modification of the immune response
Week 5 - Theoretical & Practice
Anti-tumor genes and cancer modulation
Week 6 - Theoretical & Practice
Selective replication of viruses in tumors
Week 7 - Theoretical & Practice
Antiangiogenic Gene Therapy
Week 8 - Theoretical & Practice
Medication and treatment tests-1 (Midterm)
Week 9 - Theoretical & Practice
Medication and treatment tests-2
Week 10 - Theoretical & Practice
Gene therapy vectors
Week 11 - Theoretical & Practice
Adeno viruses (ADV) and Adeno-related virus (AAV)
Week 12 - Theoretical & Practice
Retroviral vectors
Week 13 - Theoretical & Practice
Lentivirus (HIV) vectors
Week 14 - Theoretical & Practice
Gene and cellular treatments applied in oncology
Week 15 - Final Exam
Final
Assessment Methods and Criteria
Type of AssessmentCountPercent
Midterm Examination1%40
Final Examination1%60
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory131239
Lecture - Practice131239
Assignment224048
Midterm Examination124226
Final Examination148250
TOTAL WORKLOAD (hours)202
Contribution of Learning Outcomes to Programme Outcomes
PÇ-1
PÇ-2
PÇ-3
PÇ-4
PÇ-5
PÇ-6
PÇ-7
PÇ-8
PÇ-9
PÇ-10
PÇ-11
PÇ-12
PÇ-13
PÇ-14
PÇ-15
OÇ-1
5
5
5
5
4
4
4
4
5
5
5
5
5
3
5
OÇ-2
5
5
5
4
4
4
4
4
5
5
5
5
5
3
5
OÇ-3
5
5
5
4
4
4
4
4
5
5
5
5
5
3
5
OÇ-4
5
5
5
4
4
4
4
4
5
5
5
5
5
3
5
OÇ-5
5
5
5
4
4
4
4
4
5
5
5
5
5
3
5
Adnan Menderes University - Information Package / Course Catalogue
2026