Information Package / Course Catalogue
Nucleic Acids Metabolism
Course Code: TBY425
Course Type: Area Elective
Couse Group: First Cycle (Bachelor's Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 2
Prt.: 0
Credit: 2
Lab: 0
ECTS: 3
Objectives of the Course

To learn the metabolic synthesis of nucleic acids, purine and pyrimidine nucleotides and deoxyribonucleotides, to understand inhibitors of nucleotide synthesis and specific regulatory mechanisms, to grasp the importance of the regulation of nucleotide biosynthesis, learn the synthesis of specific regulating molecules, to understand the catabolism of nucleotides and their importance in cellular metabolism

Course Content

DNA and RNA structure, DNA replication, RNA synthesis, breakdown and synthesis of purines and pyrimidines, transcription and translation mechanisms.

Name of Lecturer(s)
Assoc. Prof. Emre SEVİNDİK
Learning Outcomes
1.To gain knowledge about the structure and chemistry of nucleic acid
2.To learn the synthesis of nucleic acids, destruction, repair and understand information about the control of these mechanisms
3.To learn the structure and functions of nucleic acids
4.To discuss the synthesis methods of nucleic acids
5.To learn RNA and editing mechanisms
Recommended or Required Reading
1.From Nucleic Acids Sequences to Molecular Medicine, ditors: Erdmann (Deceased), Volker A., Barciszewski, Jan (Eds.)
2.Modern Moleküler Biyoloji. 2017. Biyoloji Nihat Dilsiz. Palme Yayınevi.
3.Biyokimya. 2014. Jeremy M. Berg, John L. Tymoczko, Lubert Stryer, Çeviri Editörü : Adil Denizli,Ayşe Kevser Özden. Palme Yayınevi.
Weekly Detailed Course Contents
Week 1 - Theoretical
The chemical of DNA and RNA
Week 2 - Theoretical
DNA biosynthesis
Week 3 - Theoretical
Purine biosynthesis
Week 4 - Theoretical
Purine catabolism
Week 5 - Theoretical
Pyrimidine biosynthesis
Week 6 - Theoretical
Pyrimidine catabolism
Week 7 - Theoretical
RNA types
Week 8 - Intermediate Exam
RNA types
Week 9 - Theoretical
mRNA destruction
Week 10 - Theoretical
The processing of RNA
Week 11 - Theoretical
Transcription and Translation
Week 12 - Theoretical
DNA mutations and repair
Week 13 - Theoretical
Organelle DNAs
Week 14 - Theoretical
Disorders of nucleic acid metabolism
Week 15 - Final Exam
Final exam
Assessment Methods and Criteria
Type of AssessmentCountPercent
Midterm Examination1%40
Final Examination1%70
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory131239
Midterm Examination114115
Final Examination115116
TOTAL WORKLOAD (hours)70
Contribution of Learning Outcomes to Programme Outcomes
PÇ-1
PÇ-2
PÇ-3
PÇ-4
PÇ-5
PÇ-6
PÇ-7
PÇ-8
PÇ-9
PÇ-10
PÇ-11
OÇ-1
2
1
1
3
OÇ-2
2
1
1
1
OÇ-3
1
1
2
1
1
OÇ-4
1
1
1
1
1
OÇ-5
2
3
1
Adnan Menderes University - Information Package / Course Catalogue
2026