Information Package / Course Catalogue
Physiopathology
Course Code: BD102
Course Type: Required
Couse Group: First Cycle (Bachelor's Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 2
Prt.: 0
Credit: 3
Lab: 2
ECTS: 3
Objectives of the Course

The aim of this course is to teach the mechanisms of disease development at the cellular, tissue, and organ levels, pathophysiological processes, and their clinical implications; and to enable students to evaluate basic disease knowledge through physiological alterations and develop clinical reasoning skills.

Course Content

This course covers the cellular, tissue, and organ-level pathological changes that lead to the development of diseases in the human body and their effects on physiological functions. Fundamental pathophysiological mechanisms such as inflammation, degeneration, adaptation, cellular injury, and healing processes are addressed. In addition, system-specific disease processes are examined to explain the mechanisms underlying clinical signs and symptoms. The course aims to enable students to evaluate disease development from a holistic perspective and to develop clinical reasoning skills.

Name of Lecturer(s)
Learning Outcomes
1.Explains the pathophysiological mechanisms of diseases at the cellular, tissue, and organ levels.
2.Relates cellular injury, inflammation, and adaptation processes to their physiological bases.
3.Analyzes the development mechanisms of system-specific diseases.
4.Establishes relationships between clinical findings and underlying pathophysiological processes.
5.Develops clinical reasoning and problem-solving skills using pathophysiological knowledge.
Recommended or Required Reading
1.McCance & Huether's Pathophysiology: The Biologic Basis for Disease in Adults and Children
2.Aslan, F. E., & Olgun, N. (2017). Fizyopatoloji / Pathophysiology. Ankara: Akademisyen Kitabevi.
3.Karataş, T. (2025). Temel Patofizyoloji / Basic Pathophysiology. Ankara: Nobel Tıp Kitabevleri.
Weekly Detailed Course Contents
Week 1 - Theoretical
Introduction to pathophysiology, basic concepts, and disease development process
Week 2 - Theoretical
Cell injury and cellular adaptation mechanisms
Week 3 - Theoretical
Inflammation and inflammatory response mechanisms
Week 4 - Theoretical
Tissue injury and healing processes
Week 5 - Theoretical
Hemodynamic disorders: edema, thrombosis, embolism, shock
Week 6 - Theoretical
Immune system disorders and hypersensitivity reactions
Week 7 - Intermediate Exam
Cardiovascular pathophysiology + MIDTERM EXAM
Week 8 - Theoretical
Pathophysiology of the respiratory system+ Midterm exam evaluation, question analysis, and general review
Week 9 - Theoretical
Pathophysiology of the gastrointestinal system
Week 10 - Theoretical
Endocrine system diseases and metabolic disorders
Week 11 - Theoretical
Renal and urinary system pathophysiology
Week 12 - Theoretical
Pathophysiology of the nervous system
Week 13 - Theoretical
Pathophysiology of the musculoskeletal system
Week 14 - Final Exam
Pathophysiology of the reproductive system General review + integrated system evaluation + FINAL EXAM + FINAL EXAM EVALUATION
Assessment Methods and Criteria
Type of AssessmentCountPercent
Assignment1%1
Quiz1%1
Midterm Examination1%38
Final Examination1%60
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)