Information Package / Course Catalogue
Introduction to Electrophysiology
Course Code: BYF521
Course Type: Area Elective
Couse Group: Second Cycle (Master's Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 2
Prt.: 2
Credit: 3
Lab: 0
ECTS: 6
Objectives of the Course

The purpose of the course is to be able to tell about formation of cellular membrane potential and physical basis of this potential, recorded electrical activity samples from excitable tissues, measurements error and artifact sources with protective procedures, electro-diagnostic methods (ECG, EMG, EOG, evoked potentials).

Course Content

Formation of cellular membrane potential and physical basis of this potential, recorded electrical activity samples from excitable tissues, measurements error and artifact sources with protective procedures, electro-diagnostic methods (ECG, EMG, EOG, evoked potentials).

Name of Lecturer(s)
Prof. Mehmet Dinçer BİLGİN
Learning Outcomes
1.To be able to tell about the physical basis and formation of membrane potentials, and on properties of excitable cells
2.To comprehend the electrical properties of membranes and the action potential
3.To be able to explain and apply evoked potentials and electrophysiological measurement methods, such as ECG, EOG and GSR
4.To gain knowledge on the electrophysiological data analysis
5.To be able to explain how to measure nerve conduction velocity and compound muscle action potential
Recommended or Required Reading
1..Nuhan Puralı, Hücre elektrofizyolojisi ve görüntülemenin temelleri, Veri Medikal, Ankara, 2008.
2.Gürbüz Çelebi, Medical Physics, Barış yayınları fakülte kitapevi, İzmir 2010
3.Ferit Pehlivan, Biophysics, Hacettepe-Taş yayınevi, Ankara, 2011.
4.Guyton ve Hall, Medical Physiology, 2010
5.Şefik Dursun (ed.) Biophysics Lecture Notes, CTF Yayınevi, İstanbul, 2010.
6.E.R.Kandel et al (eds), Principles of Neural Sciences, 2000.
7.Lodish&Baltimore et al (eds.), Moleculer Cell Biology, 2004.
8.GG Matthews (ed.), Neurobiology 2000
9.J.E. Blankenship (ed.), Neurophysiology, 2003.
Weekly Detailed Course Contents
Week 1 - Theoretical
Introduction to electrophysiology
Week 1 - Practice
Electrodes and transducers
Week 2 - Theoretical
Osmosis and aquaporins
Week 2 - Practice
Osmotic events in the cell
Week 3 - Theoretical
Gibbs-Donnan equilibrium, Nerst equation, GHK rule
Week 3 - Practice
Introduction to MP 100 data analysis system
Week 4 - Theoretical
Ion channels
Week 4 - Practice
Introduction to MP 100 data analysis system
Week 5 - Theoretical
Membrane potential
Week 5 - Practice
Applications of MP 100 data analysis system
Week 6 - Theoretical
Electrical properties of membranes
Week 6 - Practice
Evaluation of data in MP 100 data analysis system
Week 7 - Theoretical
Action potential
Week 7 - Practice
Evaluation of data in MP 100 data analysis system
Week 8 - Intermediate Exam
Midterm exam
Week 9 - Theoretical
Action potential in different tissue types
Week 9 - Practice
EOG applications
Week 10 - Theoretical
Electrical properties of the heart
Week 10 - Practice
GSR applications
Week 11 - Theoretical
The basis and properties of ECG
Week 11 - Practice
ECG applications
Week 12 - Theoretical
EMG, compound muscle action potential and nerve conduction velocity
Week 12 - Practice
EMG, nerve conduction velocity in rats and the measurement of compound muscle action potential
Week 13 - Theoretical
Evoked potentials
Week 13 - Practice
Evoked potentials
Week 14 - Theoretical
Electrophysiological data analysis
Week 14 - Practice
Electrophysiological data analysis
Week 15 - Final Exam
Final exam
Assessment Methods and Criteria
Type of AssessmentCountPercent
Midterm Examination1%20
Final Examination1%50
Assignment2%10
Practice Examination1%20
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory131239
Lecture - Practice131239
Assignment2036
Laboratory131239
Reading130113
Practice Examination1022
Midterm Examination1415
Final Examination1426
TOTAL WORKLOAD (hours)149
Contribution of Learning Outcomes to Programme Outcomes
PÇ-1
PÇ-2
PÇ-3
PÇ-4
PÇ-5
PÇ-6
PÇ-7
PÇ-8
PÇ-9
PÇ-10
PÇ-11
PÇ-12
PÇ-13
PÇ-14
PÇ-15
PÇ-16
PÇ-17
PÇ-18
OÇ-1
5
5
5
4
5
3
3
4
5
5
4
2
4
2
2
5
4
5
OÇ-2
5
5
5
4
5
2
2
2
5
5
5
1
3
2
4
5
4
5
OÇ-3
5
5
5
5
5
2
2
2
5
5
5
1
4
3
4
4
4
5
OÇ-4
5
5
5
5
5
2
2
2
5
4
4
1
3
2
3
4
5
5
OÇ-5
5
5
5
5
5
3
1
2
5
5
5
1
3
2
2
4
4
5
Adnan Menderes University - Information Package / Course Catalogue
2026