Information Package / Course Catalogue
Introduction to Bioinformatics
Course Code: BİS529
Course Type: Area Elective
Couse Group: Second Cycle (Master's Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 2
Prt.: 0
Credit: 2
Lab: 0
ECTS: 4
Objectives of the Course

Providing theoretical and practical information about the molecular biological aspects of informatics systems.This course aims to develop student’s skills for data mining in descriptive repositories.

Course Content

Description and base concepts of bioinformatics. Molecular biology databases, the analysis of macromolecular sequences, hidden Markov models, genome assembly and next-generation sequencing, protein-protein interaction and networks, phylogenetics, protein structure and prediction, molecular dynamics, genetic linkage, gene expression.

Name of Lecturer(s)
Prof. Mevlüt TÜRE
Learning Outcomes
1.To be able to comprehend the importance of bioinformatics in the field of health care
2.Understand the basics of biological databases and use them in molecular biology and genetics
3.Identify comparison tools for two or more series and discuss similarity / noncompliance
4.To be able to understand the flow of information between protein-RNA and DNA and to analyze large-scale biological data using various bioinformatics based tools
5.Be able to discuss genomics, proteomics and pharmacogenetic approaches using bioinformatics tools
Recommended or Required Reading
Weekly Detailed Course Contents
Week 1 - Theoretical
Introduction to the course: DNA Databases
Week 2 - Theoretical
Protein Databases
Week 3 - Theoretical
DNA Sequencing and Assembly
Week 4 - Theoretical
Translation, Mapping and Primers
Week 5 - Theoretical
Protein Structure Web Tools
Week 6 - Theoretical
Pairwise Comparison Scoring Matrices
Week 7 - Theoretical
Database Similarity Searching
Week 8 - Intermediate Exam
Midterm exam
Week 9 - Theoretical
Multiple Alignment
Week 10 - Theoretical
Motifs, Patterns, and Profiles
Week 11 - Theoretical
Genomics - How were genomes sequenced? Genome Databases and the UCSC Browser
Week 12 - Theoretical
Genome Browsers 2 Comparative Genomics
Week 13 - Theoretical
Dealing with Gene Lists: Gene Ontology
Week 14 - Theoretical
Introduction to Phylogenetic Analysis
Week 15 - Theoretical
Literature review and discussion
Week 16 - Final Exam
Final exam
Assessment Methods and Criteria
Type of AssessmentCountPercent
Midterm Examination1%40
Final Examination1%60
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory140228
Reading140114
Individual Work140228
Midterm Examination110111
Final Examination115217
TOTAL WORKLOAD (hours)98
Contribution of Learning Outcomes to Programme Outcomes
PÇ-1
PÇ-2
PÇ-3
PÇ-4
PÇ-5
PÇ-6
PÇ-7
PÇ-8
PÇ-9
PÇ-10
OÇ-1
5
3
3
3
4
3
4
3
3
3
OÇ-2
5
5
5
3
4
5
4
4
5
4
OÇ-3
OÇ-4
OÇ-5
Adnan Menderes University - Information Package / Course Catalogue