The aim of this subject to ensure that the best available evidence is carefully, carefully and intelligently used when decision-making in the main objective patient's diagnosis and treatment process.

Define evidence-based medicine and its steps, searching the literature by keywords, definition, calculation and interpretation of the most common measures of association (relative risk, NNT) used in clinical trials, identification of the research designs used in medical studies, gold standard, “double-blinding” and independence in diagnostic tests, calculation and interpretation of diagnostic test performance (sensitivity, specificity,accuracy, etc.), description of the methodological principles and steps of a systematic review of the literature.