Information Package / Course Catalogue
Basic Oncology
Course Code: ONK501
Course Type: Required
Couse Group: Second Cycle (Master's Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 2
Prt.: 2
Credit: 3
Lab: 0
ECTS: 8
Objectives of the Course

The aim of this course is to define the basic oncology and to teach the molecular basis of carcinogenesis and anticancer treatment with examples from special cancer types.

Course Content

Carcinogenesis, cell cycle and cancer relationship, the role of differentiation and transformation in cancer development and molecular mechanisms. Cell Death Mechanisms, Angiogenesis, Invasion and Metastasis, Significance of Signal Pathways in Cancer, Oncogen and Tumor Suppressor The importance of genes in cancer diagnosis, treatment and follow-up. In the courses, cancer cell culture, Western blot application, DNA, RNA isolation from tumor tissue, real time PCR mutation analysis in cancer diagnosis will be explained.

Name of Lecturer(s)
Learning Outcomes
1.To learn the basic oncological approach
2.To examine the carcinogenesis-tumorogenesis steps
3.Discuss genetic changes and mutations in cancer.
4.To review cancer-host and immune system relationships
5.Discuss differences in anticancer treatment
Recommended or Required Reading
1.Genetics: from genes to genomes, 5th edition, Hartwell LH, Goldberg ML, 2014, McGraw Hill Education.
2.Color atlas of genetics, 4th edition, Passarge E, 2012, Thieme
Weekly Detailed Course Contents
Week 1 - Theoretical & Practice
Introduction to Basic Oncology
Week 2 - Theoretical & Practice
Etiology of Cancer
Week 3 - Theoretical & Practice
Cell differentiation and transformation
Week 4 - Theoretical & Practice
Importance of signaling pathways in cancer
Week 5 - Theoretical & Practice
Cancer Related Genes: Oncogen and Tumor Suppressing Genes
Week 6 - Theoretical & Practice
Importance of Staging in Cancer
Week 7 - Theoretical & Practice
Molecular Mechanisms in Specific Cancer Types-1
Week 8 - Theoretical & Practice
Molecular Mechanisms in Specific Cancer Types-2 (Mid-term exam)
Week 9 - Theoretical & Practice
Cancer-causing Genetic Changes: Mutations
Week 10 - Theoretical & Practice
DNA Damage and Repair in Cancer
Week 11 - Theoretical & Practice
Epigenetic Regulation and Changes in Cancer
Week 12 - Theoretical & Practice
Cancer and Immune System
Week 13 - Theoretical & Practice
Cancer Cell and Host Relationships (Angiogenesis, Invasion and Metastasis)
Week 14 - Theoretical & Practice
Molecular Basis of Anticancer Therapy
Week 15 - Final Exam
Final exam
Assessment Methods and Criteria
Type of AssessmentCountPercent
Assignment1%5
Quiz1%5
Midterm Examination1%20
Final Examination1%70
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory142256
Lecture - Practice142256
Assignment1819
Quiz112012
Midterm Examination118220
Final Examination148250
TOTAL WORKLOAD (hours)203
Contribution of Learning Outcomes to Programme Outcomes
PÇ-1
PÇ-2
PÇ-3
PÇ-4
PÇ-5
PÇ-6
PÇ-7
PÇ-8
PÇ-9
PÇ-10
PÇ-11
PÇ-12
PÇ-13
PÇ-14
OÇ-1
4
3
5
3
4
3
5
5
4
3
OÇ-2
4
3
5
4
4
5
5
5
OÇ-3
4
3
5
4
4
5
5
5
OÇ-4
3
4
5
4
4
5
5
5
OÇ-5
4
5
5
4
4
5
5
5
Adnan Menderes University - Information Package / Course Catalogue
2026