
| Course Code | : ONK526 |
| Course Type | : Area Elective |
| Couse Group | : Second Cycle (Master's Degree) |
| Education Language | : Turkish |
| Work Placement | : N/A |
| Theory | : 3 |
| Prt. | : 0 |
| Credit | : 3 |
| Lab | : 0 |
| ECTS | : 8 |
To teach the concepts related to signal transduction and mechanism in cancer molecular biology and to explain their reflection to the clinic.
Understanding of signal transduction, ligands, receptors and their concepts in cancer molecular biology. Cancer cell division and signaling changes in life, cancer signal transduction systems and molecular targets, control of transcriptional regulators, understanding the signaling mechanism of cancer.
| 1. | Have in-depth knowledge about signal transduction in cancer and signaling pathways in cancer cells. |
| 2. | Discuss cancer-specific signal transduction and transcription factors. |
| 3. | Knows the differences of signal transduction mechanisms between different cancer types |
| 4. | Discuss the clinical implications of signaling pathways |
| 5. | Know molecular targets in cancer treatment and discuss the clinical effects of signal blocking |
| 1. | Molecular Biology in Cancer Medicine. Razelle Kurzrock, Moshe Talpaz, Martin Dunitz 1995. |
| 2. | Tumor Models in Cancer Research Beverly A. Teicher Humana Pres 2002 |
| 3. | AJCC Cancer Staging Handbook.Irvin D. Fleming. Lippincott Willams & Wilkins, 2013 |
| 4. | Manual of Clinical Oncology. D.K. Hossfeld, C.D. Sherman, R.R. Love, F.X. Bosch Springer- Verlag, 1990 Fith Edition. |
| 5. | Pathologic Basis of Disease. Vinay Kumar, Abul K. Abbas, Nelson Fausto, Elsevier Saunderss, 2015 Seventh Edition |
| 6. | Molecular Mechanism of Cancer. Georg F. Weber, Springer, 2007 |
| 7. | The Biology of Cancer Robert A. Weinberg, Gariand Science 2014 |
| Type of Assessment | Count | Percent |
|---|---|---|
| Assignment | 1 | %5 |
| Quiz | 1 | %5 |
| Midterm Examination | 1 | %20 |
| Final Examination | 1 | %70 |
| Activities | Count | Preparation | Time | Total Work Load (hours) |
|---|---|---|---|---|
| Lecture - Theory | 14 | 1 | 2 | 42 |
| Lecture - Practice | 14 | 1 | 2 | 42 |
| Assignment | 1 | 18 | 1 | 19 |
| Quiz | 1 | 18 | 1 | 19 |
| Midterm Examination | 1 | 24 | 2 | 26 |
| Final Examination | 1 | 48 | 2 | 50 |
| TOTAL WORKLOAD (hours) | 198 | |||
PÇ-1 | PÇ-2 | PÇ-3 | PÇ-4 | PÇ-5 | PÇ-6 | PÇ-7 | PÇ-8 | PÇ-9 | PÇ-10 | PÇ-11 | PÇ-12 | PÇ-13 | PÇ-14 | |
OÇ-1 | 3 | 3 | 1 | 5 | 2 | 3 | 4 | 3 | 3 | 5 | 4 | 4 | ||
OÇ-2 | 3 | 3 | 1 | 5 | 2 | 3 | 4 | 3 | 3 | 5 | 4 | 4 | ||
OÇ-3 | 3 | 3 | 1 | 5 | 2 | 3 | 4 | 3 | 3 | 5 | 4 | 4 | ||
OÇ-4 | 3 | 3 | 1 | 5 | 2 | 3 | 4 | 3 | 3 | 5 | 4 | 4 | ||
OÇ-5 | 3 | 3 | 1 | 5 | 2 | 3 | 4 | 3 | 3 | 5 | 5 | 4 | ||