Information Package / Course Catalogue
| Course Code | : ONK529 |
| Course Type | : Area Elective |
| Couse Group | : Second Cycle (Master's Degree) |
| Education Language | : Turkish |
| Work Placement | : N/A |
| Theory | : 2 |
| Prt. | : 0 |
| Credit | : 2 |
| Lab | : 0 |
| ECTS | : 6 |
The aim of this course is to give an in-depth knowledge of invasion and metastasis in cancer molecular biology and their reflection to the clinic.
Difference of cancer cell from normal cell, changes in cell membrane in cancer, intercellular communication changes in cancer tissue, cell adhesion molecules and cancer, angiogenesis, stages of metastasis development and metastasis related genes, molecular properties and their reflection to the clinic will be explained.
| 1. | Explain the concepts of invasion and metastasis in cancer |
| 2. | Discuss the stages of metastasis in cancer |
| 3. | Examine the mechanisms and genes associated with metastasis |
| 4. | Discuss the reflection of metastasis to the clinic |
| 5. | To learn the role of angiogenesis and lymphangiogenesis in cancer |
| 6. | Knows the role of epithelial-mesenchymal transition in cancer metastasis |
| 1. | Introduction to Cancer Metastasis, Aamir Ahmad, Academic Press, 2017, ISBN 978-0-12-804003-4 |
| 2. | The Biology of Cancer, Robert A. Weinberg, 2nd edition, ISBN-13: 978-0815342205, 2013 |
| 3. | Molecular Biology in Cancer Medicine. Razelle Kurzrock, Moshe Talpaz, Martin Dunitz 1995. |
| 4. | Tumor Models in Cancer Research Beverly A. Teicher Humana Pres 2002 |
| 5. | AJCC Cancer Staging Handbook.Irvin D. Fleming. Lippincott Willams & Wilkins 2013 |
| 6. | Manual of Clinical Oncology. D.K. Hossfeld, C.D. Sherman, R.R. Love, F.X. Bosch Springer- Verlag, 1990 Fith Edition. |
| 7. | Pathologic Basis of Disease. Vinay Kumar, Abul K. Abbas, Nelson Fausto, Elsevier Saunderss, 2015 Seventh Edition |
| 8. | Molecular Mechanism of Cancer. Georg F. Weber, Springer, 2007 |
| Type of Assessment | Count | Percent |
|---|---|---|
| Assignment | 1 | %5 |
| Quiz | 1 | %5 |
| Midterm Examination | 1 | %20 |
| Final Examination | 1 | %70 |
| Activities | Count | Preparation | Time | Total Work Load (hours) |
|---|---|---|---|---|
| Lecture - Theory | 14 | 1 | 2 | 42 |
| Assignment | 1 | 18 | 1 | 19 |
| Quiz | 1 | 8 | 1 | 9 |
| Midterm Examination | 1 | 24 | 2 | 26 |
| Final Examination | 1 | 48 | 2 | 50 |
| TOTAL WORKLOAD (hours) | 146 | |||
PÇ-1 | PÇ-2 | PÇ-3 | PÇ-4 | PÇ-5 | PÇ-6 | PÇ-7 | PÇ-8 | PÇ-9 | PÇ-10 | PÇ-11 | PÇ-12 | PÇ-13 | PÇ-14 | |
OÇ-1 | 3 | 3 | 4 | 3 | 3 | 3 | 4 | 3 | 4 | |||||
OÇ-2 | 3 | 3 | 4 | 3 | 3 | 3 | 4 | 3 | 4 | |||||
OÇ-3 | 3 | 3 | 4 | 3 | 3 | 3 | 4 | 3 | 4 | |||||
OÇ-4 | 3 | 3 | 4 | 3 | 3 | 3 | 4 | 4 | 4 | |||||
OÇ-5 | 3 | 3 | 4 | 3 | 3 | 3 | 4 | 3 | 4 | |||||
OÇ-6 | 3 | 3 | 4 | 3 | 3 | 3 | 4 | 3 | 4 | |||||