Information Package / Course Catalogue
Hallmarks of Cancer
Course Code: ONK536
Course Type: Area Elective
Couse Group: Second Cycle (Master's Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 3
Prt.: 0
Credit: 3
Lab: 0
ECTS: 7
Objectives of the Course

The aim of this course is to comprehend the differences of cancer cell from normal cell with morphological and biological point of view.

Course Content

Normal tissue characteristics, Normal Cell Morphology, Cancer precursor, cellular changes, Carcinoma in situ, Properties of Cancer Cell, Invasion and Metastasis, Morphology of Carcinomas and Sarcomas, Morphology of Hematological Cancers, Cell Death, Cancer Differentiation, Cancer Proliferation, Cancer Inflammation, Cancer Stroma aims to understand the issues.

Name of Lecturer(s)
Learning Outcomes
1.To understand the difference between cancer cells and normal cells
2.To be able to comprehend cancer precursor changes in multistep carcinogenesis
3.To be able to explain morphological differences between different types of cancer
4.Describe the characteristics of cancer cells in proliferation, cell death, differentiation, invasion and metastatic process
5.To understand the relationship between cancer cell and stroma
Recommended or Required Reading
1.Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011;144(5):646-74.
2. Molecular Mechanism of Cancer. Georg F. Weber, Springer 2007
3.The Biology of Cancer Robert A. Weinberg, Gariand Science 2007
Weekly Detailed Course Contents
Week 1 - Theoretical
Normal tissue properties
Week 2 - Theoretical
Normal Cell Morphology
Week 3 - Theoretical
Precancerous cellular changes and carcinoma in situ
Week 4 - Theoretical
Cancer Cell Properties-morphological overview
Week 5 - Theoretical
Cancer Cell Properties-Biochemical Overview
Week 6 - Theoretical
Differentiation and Cancer
Week 7 - Theoretical
Proliferation and Cancer
Week 8 - Theoretical
Angiogenesis (Mid-term exam)
Week 9 - Theoretical
Invasion and Metastasis
Week 10 - Theoretical
Cell death and cancer
Week 11 - Theoretical
Morphology of Hematologic Cancers
Week 12 - Theoretical
Morphology of Carcinomas and Sarcomas
Week 13 - Theoretical
Inflammation and Cancer
Week 14 - Theoretical
Cancer Stroma Features
Week 15 - Final Exam
Final exam
Assessment Methods and Criteria
Type of AssessmentCountPercent
Assignment1%5
Quiz1%5
Midterm Examination1%20
Final Examination1%70
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory141356
Assignment118119
Quiz118119
Midterm Examination124226
Final Examination148250
TOTAL WORKLOAD (hours)170
Contribution of Learning Outcomes to Programme Outcomes
PÇ-1
PÇ-2
PÇ-3
PÇ-4
PÇ-5
PÇ-6
PÇ-7
PÇ-8
PÇ-9
PÇ-10
PÇ-11
PÇ-12
PÇ-13
PÇ-14
OÇ-1
5
5
5
5
5
1
2
2
5
1
3
5
2
5
OÇ-2
5
5
5
5
5
1
2
2
5
1
3
5
2
5
OÇ-3
5
5
5
5
5
1
2
2
5
1
3
5
2
5
OÇ-4
5
5
5
5
5
1
2
2
5
1
3
5
2
5
OÇ-5
5
5
5
5
5
1
2
2
5
1
3
5
2
5
Adnan Menderes University - Information Package / Course Catalogue
2026