Information Package / Course Catalogue
Toxicogenetics and Applications
Course Code: VFT556
Course Type: Area Elective
Couse Group: Second Cycle (Master's Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 1
Prt.: 2
Credit: 2
Lab: 0
ECTS: 4
Objectives of the Course

Learn about toxic factors in the relationship between genetic and hereditary disorders, and epidemiological frequency effects the usefulness of toxic substances and/or detrimental effects caused by toxic substances and substances and properties of the effects of genetic mutation, teratogenicity and carcinogenicity testing and practical.

Course Content

Toxic factors in the relationship between genetic and hereditary disorders, and epidemiological frequency effects the usefulness of toxic substances and/or detrimental effects caused by toxic substances and substances and properties of the effects of genetic mutation, teratogenicity and carcinogenicity testing and practical are examined.

Name of Lecturer(s)
Learning Outcomes
1.Learn about the relationship between toxic substances and genetically.
2.Learn about the genetic effects of toxic substances and their properties.
3.Gain information about the toxicity tests and applications.
4.To find out and use resources about the profession in the area.
5.To give lectures and/or presentations and discuss with professionals in the area.
Recommended or Required Reading
1.Modern Toxicology, Ernest HODGSON, Patricia E. LEVI; Elsevier, London, 1987.
2.Principles and Methods of Toxicology, A. Wallace HAYES, Edward BROTHERS; Ann Arbor Press, 2001.
3.Handbook of Experimental Pharmacology – 199; Comparative and Veterinary Pharmacology, Fiona CUNNINGHAM, Jonathan ELLIOTT, Peter LEES (Editors); Springer Press, 2009.
Weekly Detailed Course Contents
Week 1 - Theoretical
Basic concepts in genetic structure
Week 1 - Practice
Method to determine the applications guide
Week 2 - Theoretical
Evaluation of the contribution of genetic and environmental factors
Week 2 - Practice
Method to determine the applications guide
Week 3 - Theoretical
Genetic damage, and markers of the effects
Week 3 - Practice
Selection of genetic testing and study design
Week 4 - Theoretical
DNA damage repair, and genetic risk assessment process
Week 4 - Practice
Selection of genetic testing and study design
Week 5 - Theoretical
Fields of toxicogenetic
Week 5 - Practice
Genetic hazard and risk assessment methods
Week 6 - Theoretical
The effects of toxic substances - or inhibition of enzyme induction
Week 6 - Practice
Genetic hazard and risk assessment methods
Week 7 - Theoretical
Article discussion
Week 7 - Practice
Paper presentation
Week 8 - Theoretical
Mutation (Midterm exam)
Week 9 - Theoretical
The mutagenic properties of substances
Week 9 - Practice
Mutagenicity tests and applications
Week 10 - Theoretical
Mutation, the mutagenic properties of substances
Week 10 - Practice
Mutagenicity tests and applications
Week 11 - Theoretical
Teratogenicity, teratogenic substances and their properties
Week 11 - Practice
Teratogenic tests and applications
Week 12 - Theoretical
Teratogenicity, teratogenic substances and their properties
Week 12 - Practice
Teratogenic tests and applications
Week 13 - Theoretical
Carcinogenicity, carcinogenic substances and their properties
Week 13 - Practice
Tests and applications of carcinogenic
Week 14 - Theoretical
Carcinogenicity, carcinogenic substances and their properties
Week 14 - Practice
Tests and applications of carcinogenic
Week 15 - Final Exam
Final exam
Assessment Methods and Criteria
Type of AssessmentCountPercent
Presentation1%5
Verbal Examination1%5
Midterm Examination1%20
Final Examination1%70
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory142142
Lecture - Practice141242
Midterm Examination1314
Final Examination1617
TOTAL WORKLOAD (hours)95
Contribution of Learning Outcomes to Programme Outcomes
PÇ-1
PÇ-2
PÇ-3
PÇ-4
PÇ-5
PÇ-6
PÇ-7
PÇ-8
PÇ-9
PÇ-10
PÇ-11
PÇ-12
OÇ-1
5
4
4
OÇ-2
5
4
5
OÇ-3
5
5
5
5
OÇ-4
5
5
5
OÇ-5
4
4
5
5
5
5
Adnan Menderes University - Information Package / Course Catalogue
2026