Information Package / Course Catalogue
Molecular Basics of Inheritance
Course Code: ZBY602
Course Type: Area Elective
Couse Group: Third Cycle (Doctorate Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 2
Prt.: 2
Credit: 3
Lab: 0
ECTS: 8
Objectives of the Course

Understanding the control of genetic information at the cell level of protein production from DNA

Course Content

DNA structure and analysis, transformation studies, Hershey-Chase Experiment, transfection experiments, DNA distribution, mutation formation, recombinant DNA studies, nucleotides, nucleoside diphosphates and triphosphates, polynucleotides Base composition and related studies, X- Watson-Crick model, different forms of DNA, Absorption of ultraviolet light, Precipitation behavior, Denaturation and renaturation of nucleic acids,

Name of Lecturer(s)
Learning Outcomes
1.Based on doctoral qualifications, he / she knows current and forward-looking genetic and advanced technology knowledge, genetic mechanisms, and develops a professional approach to original planning and / or research, and makes inferential and inferential deductions
2.Knows the structure of DNA and the ways in which the structure of DNA is revealed
3.Knows the triple nature of the genetic code, the degenerate password and the Wobble hypothesis, start termination and suppression, the promoter regions, the template and Sigma subunit, the effective elements of RNA synthesis and start to know
4.Have knowledge about DNA damage and repair and DNA damage detection
5.Knows the epigenetic mechanisms
Recommended or Required Reading
1.Khatib H. (2012) Livestock Epigenetics. Wiley-Blackwell Publishing. USA
2.Klug, W. S., Cummings, M. R., Spencer, C. A., & Palladino, M. A. (2011). Concepts of genetics. Pearson Higher Ed.
Weekly Detailed Course Contents
Week 1 - Theoretical & Practice
Structure and analysis of DNA, transformation studies, Hershey-Chase Experiment, transfection experiments, mutation generation, Recombinate DNA studies
Week 2 - Theoretical & Practice
Central dogma
Week 3 - Theoretical & Practice
Nucleotides, nucleoside diphosphates and triphosphates, polynucleotides
Week 4 - Theoretical & Practice
Base composition and related studies, X-ray diffraction analysis, Watson-Crick model
Week 5 - Theoretical & Practice
Different forms of DNA, Absorption of Ultraviolet Light, Denaturation and renaturation of nucleic acids,
Week 6 - Theoretical & Practice
Molecular hybridization, recombination kinetics and repetitive DNA, Electrophoresis of nucleic acids
Week 7 - Theoretical & Practice
Proof-reading activity in replication
Week 8 - Theoretical & Practice
Proof-reading activity in replication
Week 9 - Theoretical & Practice
DNA recombination and specific enzymes
Week 10 - Theoretical & Practice
Triple nature of genetic code, Wobble hypothesis, non-overlapping nature of code, unstable and degenerate nature of code, homopolymer codes, repeated copolymers
Week 11 - Theoretical & Practice
Translation steps of mRNA,one gene-one enzyme hypothesis, shuffling exons and origin of protein regions
Week 12 - Theoretical & Practice
Structural genes, regulator genes, operons
Week 13 - Theoretical & Practice
Transcription factors
Week 14 - Theoretical & Practice
alternative splicing in mRNA, control of mRNA stability, post-transcription mechanisms, DNA methylation
Assessment Methods and Criteria
Type of AssessmentCountPercent
Midterm Examination1%30
Final Examination1%70
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory144284
Lecture - Practice144284
Midterm Examination112113
Final Examination112113
TOTAL WORKLOAD (hours)194
Contribution of Learning Outcomes to Programme Outcomes
PÇ-1
PÇ-2
PÇ-3
PÇ-4
PÇ-5
OÇ-1
5
4
5
4
3
OÇ-2
5
5
4
5
5
OÇ-3
4
4
4
3
4
OÇ-4
3
3
2
3
4
OÇ-5
5
5
4
4
5
Adnan Menderes University - Information Package / Course Catalogue
2026