Information Package / Course Catalogue
Advanced Molecular Genetic Methods and Application Areas
Course Code: ZBY604
Course Type: Area Elective
Couse Group: Third Cycle (Doctorate Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 2
Prt.: 2
Credit: 3
Lab: 0
ECTS: 8
Objectives of the Course

Within the scope of this course, to learn the properties of nucleic acid molecules that form the basis of genetic information of organisms, to understand the organization and packaging of chromosomes in prokaryotic and eukaryotic organisms, to understand how processes such as DNA replication, transcription and translation, which are essential for reproduction and gene expression, take place in prokaryotic and eukaryotic organisms and to be able to compare them. It is aimed to understand the genetic code and its basics, to understand the regulation mechanisms of gene expression before transcription, initiation of transcription and initiation of translation, to comprehend the regulatory proteins that play a role in the regulation of gene expression and the principles of operation, to understand issues such as cell signaling and embryonic development.

Course Content

Comparison of gene control levels and post-transcriptional events with cell type-specific gene regulation and their practical use

Name of Lecturer(s)
Learning Outcomes
1.To have knowledge about DNA as genomic material, DNA sequences and properties of nucleic acids
2.To know the organization and arrangement of prokaryotic and eukaryotic genome
3.To be able to distinguish the developmental stages of information coming from nucleic acids in prokaryotic and eukaryotic organisms
4.To be able to solve the basic problems of molecular genetics
5.To know the applications of molecular genetics
Recommended or Required Reading
1.Gene Control, David S. Latchman, Garland Science, Taylor & Francis Group, ISBN:978-08153-6516-6.
2.Watson, Baker, Bell, Gann, Levine, Losick, Molecular Biology of the Gene, 6th Edition, Pearson Publications, 2008
3.Turner, McLennan, Bates, White, Moleküler Biyoloji, Önemli Notlar, Çeviri editörü Prof.Dr. Muhsin Konuk, Nobel Kitapevi, 2004
4.Russell, iGenetics : A Molecular Approach, 3rd Edition, Pearson Publications, 2009
5.Eliot, Ladomery, Molecular Biology of RNA, Oxford Publications, 2011
Weekly Detailed Course Contents
Week 1 - Theoretical & Practice
Gene Control Levels and Techniques
Week 2 - Theoretical & Practice
Chromatin Structure and molecular steps of chromosome packaging
Week 3 - Theoretical & Practice
The role of chromatin structure in the regulation of gene expression
Week 4 - Theoretical & Practice
Transcription of RNA
Week 5 - Theoretical & Practice
Transcription of RNA
Week 6 - Theoretical & Practice
Post-transcriptional events and regulation
Week 7 - Theoretical & Practice
Post-transcriptional events and regulation
Week 8 - Theoretical & Practice
Gene Control and the Cellular Signaling Pathway
Week 9 - Theoretical & Practice
Gene Control and the Cellular Signaling Pathway
Week 10 - Theoretical & Practice
Gene Control in Embryonic Development
Week 11 - Theoretical & Practice
Control of cell type-specific gene expression
Week 12 - Theoretical & Practice
Control of cell type-specific gene expression
Week 13 - Theoretical & Practice
Gene Regulation
Week 14 - Theoretical & Practice
Gene Regulation
Assessment Methods and Criteria
Type of AssessmentCountPercent
Midterm Examination1%30
Final Examination1%70
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory144284
Lecture - Practice144284
Midterm Examination112113
Final Examination112113
TOTAL WORKLOAD (hours)194
Contribution of Learning Outcomes to Programme Outcomes
PÇ-1
PÇ-2
PÇ-3
PÇ-4
PÇ-5
OÇ-1
4
5
5
3
5
OÇ-2
5
5
4
4
4
OÇ-3
4
3
3
4
3
OÇ-4
5
5
5
5
5
OÇ-5
5
5
5
5
5
Adnan Menderes University - Information Package / Course Catalogue
2026