Information Package / Course Catalogue
Protein Structure and Functions in Agricultural Biotechnology
Course Code: ZBY644
Course Type: Area Elective
Couse Group: Third Cycle (Doctorate Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 3
Prt.: 0
Credit: 3
Lab: 0
ECTS: 8
Objectives of the Course

Structural Genomics and Proteomics, Protein three-dimensional structures, X-Ray and NMR techniques, programs and applications related to imaging the three-dimensional structures of proteins, Structure and architecture of proteins, Protein folding, Hierarchical structures of proteins, Structural basis of protein functions, Control and regulation mechanisms of protein functions , Key motor proteins, Protein degradation, Structural and functional genomics, Homology-based modeling examination of the workings

Course Content

Structural Genomics and Proteomics, Protein three-dimensional structures, X-Ray and NMR techniques, programs and applications related to imaging the three-dimensional structures of proteins, Structure and architecture of proteins, Protein folding, Hierarchical structures of proteins, Structural basis of protein functions, Control and regulation mechanisms of protein functions , Key motor proteins, Protein degradation, Structural and functional genomics, Homology-based modelling, bioinformatics and in silico analysis methods

Name of Lecturer(s)
Learning Outcomes
1.Distinguish the relationships between the structures and functions of proteins at the molecular level.
2.Applies its ability to view protein structure at the atomic level and to solve problems in new areas such as rational pharmacological drug design.
3.Provides analysis, modification and visualization of physical and chemical bonds and interactions between atoms and groups, which play a role in the gaining of different hierarchical structures of proteins, by using special programs, and uses this information for the economical and effective design of laboratory experiments in the future.
4.Learns bioinformatics databases and tools. Experiences in silico analysis methods
5.Knows protein and gene-oriented bioinformatics literature well and learns to project
Recommended or Required Reading
1.Protein Structure and Fuction, Petsko G, A and Ringe D; Introduction to protein structure, Branden C; Introduction to Protein Architecture, Lesk A, M; Lehninger Principles of Biochemistry,David L. Nelson, Michael M. Cox. M. Cox http://structome.org/index.php/Main_Page http://spdbv.vital-it.ch/ http://dock.compbio.ucsf.edu/DOCK_6/index.htm
Weekly Detailed Course Contents
Week 1 - Theoretical
Structural Genomics and Proteomics
Week 2 - Theoretical
Protein three-dimensional structures; X-Ray and NMR techniques
Week 3 - Theoretical
Visualization of the three-dimensional structures of proteins
Week 4 - Theoretical
Structure and architecture of proteins; protein folding
Week 5 - Theoretical
Hierarchical structures of proteins
Week 6 - Theoretical
Structural basis of protein functions
Week 7 - Theoretical
Control and regulation mechanisms of protein functions
Week 8 - Theoretical
Techniques for determining protein functions
Week 9 - Theoretical
Key motor proteins and their degradation.
Week 10 - Theoretical
Structural and functional genomics, Modeling based on homology
Week 11 - Theoretical
3-D modeling based on structural profile and Rosetta.
Week 12 - Theoretical
Methods for detecting ligand binding sites and sequences of catalytic importance
Week 13 - Theoretical
Gene Regulation and Protein structure-function relationships
Week 14 - Theoretical
Gene Regulation and Protein structure-function relationships
Assessment Methods and Criteria
Type of AssessmentCountPercent
Midterm Examination1%30
Final Examination1%70
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory144398
Assignment103140
Presentation 103140
Midterm Examination110111
Final Examination110111
TOTAL WORKLOAD (hours)200
Contribution of Learning Outcomes to Programme Outcomes
PÇ-1
PÇ-2
PÇ-3
PÇ-4
PÇ-5
OÇ-1
5
5
5
4
5
OÇ-2
5
5
5
4
5
OÇ-3
5
4
5
4
4
OÇ-4
5
4
5
4
4
OÇ-5
4
4
5
5
4
Adnan Menderes University - Information Package / Course Catalogue
2026