Information Package / Course Catalogue
Advanced Microbial Genetics
Course Code: ZBY636
Course Type: Area Elective
Couse Group: Third Cycle (Doctorate Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 3
Prt.: 0
Credit: 3
Lab: 0
ECTS: 8
Objectives of the Course

1. The aim of this course is to gain advanced knowledge about the basic and important subjects of bacterial genetics, 2. Adaptation of this information to Recombinant DNA and Agricultural Biotechnology applications, 3. To have knowledge about current developments and applications of microbial genetics

Course Content

The basic terms and definitions used in microbial genetics, types of mutations and genetic analysis, plasmids, molecular mechanisms of bacterial conjugations, transformations, development of natural competans and transductions, genetics of bacteriophage, transpositions and integrons, global regulatory mechanisms and laboratuvar adaptation of these informatin

Name of Lecturer(s)
Learning Outcomes
1.Ph.D. students who successfully pass this course know I. )The basic terms and definitions used in microbial genetics.
2.II. Types and mechanisms of mutations and genetic analysis.
3.III. Structure and classifications of plazmids, molecular mechanisms of plazmid replication and kontrol systems, mechanims to prevent the curing of plasmids.
4.IV. Moleküler mechanisms of microbial cojugations and control systems. Applications of conjugations, chromosome mapping by Hfr crossing.
5.V. Moleküler mechanisms of microbial transformations and control systems. Molecular mechanisms of development of natural competence.
6.V. Moleküler mechanisms of microbial transformations and control systems. Molecular mechanisms of development of natural competence.
7.VII. Types and structures of transpsons, types and regulation of transpositions. Structures of Integrons. Know the roles and importance of transposon and integrons in the evolution.
8.VIII. Mechanisms of homolok and site-spesific rekombinations. The role site –specific recombinations as in the case of gene regulations.
9.IX. Molecular mechanisms of global regulatory systems. How microbes adapt to environment and talk to each other.
10.X. New trends and applications in microbial genetics.
Recommended or Required Reading
1.Molecular Genetics of Bacteria, Jeremy W. Dale, Simon F. Park ISBN: 978-0-470-74184-9
2.Snyder, L., Champness W., 2007, Molecular Genetics of Bacteria (3th Edition),ASM Press , Washington
3.Maloy SR, Cronan JE, Freifelder D, 1994, Microbial Genetics, Jones and Bartlett Publishers
4.Watson JD, Baker, T.A., Bell, S.P., Gann, A., Levine, M.,Losick, R. 2007. Molecular Biology of the Gene, 6th. Ed., Pearson Benjamin Cummings Publishing Company ve Cold Spring Harbour Laboratory Press, New York
Weekly Detailed Course Contents
Week 1 - Theoretical
Introduction to microbial genetics: used general terms and definitions
Week 2 - Theoretical
Mutations and mutegens: types and mode of actions
Week 3 - Theoretical
Genetic analysis: complementations and linkage analysis
Week 4 - Theoretical
Plazmids: structure and classifications
Week 5 - Theoretical
Plazmidler: replications and regulation mechanisims, mechanims to prevent the curing of plasmids
Week 6 - Theoretical
Bacterial konjugation
Week 7 - Theoretical
Bacterial trasnformations: development of natural competance
Week 8 - Theoretical
Genetics of bacteriophage: general and specialized transductions
Week 9 - Theoretical
Genetics of bacteriophage: general and specialized transductions
Week 10 - Theoretical
Transpositions and integrons
Week 11 - Theoretical
Homolog and site-specific recombinations
Week 12 - Theoretical
Global Regulatory mechanisms
Week 13 - Theoretical
Two compenent regulatory systems
Week 14 - Theoretical
Quorum Sensing gene regulation systems
Assessment Methods and Criteria
Type of AssessmentCountPercent
Midterm Examination1%30
Final Examination1%70
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory1491140
Assignment56240
Midterm Examination112113
Final Examination112113
TOTAL WORKLOAD (hours)206
Contribution of Learning Outcomes to Programme Outcomes
PÇ-1
PÇ-2
PÇ-3
PÇ-4
PÇ-5
OÇ-1
5
4
3
3
3
OÇ-2
5
4
4
3
3
OÇ-3
4
4
4
4
3
OÇ-4
5
4
4
3
3
OÇ-5
5
5
3
4
4
OÇ-6
5
5
5
4
4
OÇ-7
3
4
4
5
5
OÇ-8
5
5
4
4
3
OÇ-9
3
3
4
4
5
OÇ-10
5
5
5
5
5
Adnan Menderes University - Information Package / Course Catalogue
2026