Information Package / Course Catalogue
Pharmacogenetics and Applications
Course Code: VFT674
Course Type: Area Elective
Couse Group: Third Cycle (Doctorate Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 1
Prt.: 2
Credit: 2
Lab: 0
ECTS: 6
Objectives of the Course

To be informed about pharmacogenetics, their genetic structure their responses to drugs due to existing variations with changes in its metabolism of drugs involved or the effective functioning of the mechanism of the drug in some people, the usefulness of the genetic differences in the structures and/or harmful.

Course Content

Pharmacogenetics; their genetic structure their responses to drugs due to existing variations evaluate changes of the drugs involved in its metabolism, or the effective functioning of the mechanism of the drug in some people, the usefulness of the genetic differences in the structures and/or harmful effects are examined.

Name of Lecturer(s)
Learning Outcomes
1.Learn about genetic differences in humans and animals and their responses to drugs
2.To obtain information on genetic structures in the metabolism of drugs.
3.Learn about the harmful effects of drugs in humans and animals.
4.To obtain information on pharmacogenetic testing and application areas.
5.To learn knowledge and propose suggestions on the area
Recommended or Required Reading
1.Principles and Methods of Toxicology, A. Wallace HAYES, Edward BROTHERS; Ann Arbor Press, 2001.
2.Modern Toxicology, Ernest HODGSON, Patricia E. LEVI; Elsevier, London, 1987.
3.Handbook of Experimental Pharmacology – 199; Comparative and Veterinary Pharmacology, Fiona CUNNINGHAM, Jonathan ELLIOTT, Peter LEES (Editors); Springer Press, 2009.
Weekly Detailed Course Contents
Week 1 - Theoretical
Basic concepts in genetic structure
Week 1 - Practice
Method to determine the applications guide
Week 2 - Theoretical
Evaluation of the contribution of genetic and environmental factors
Week 2 - Practice
Method to determine the applications guide
Week 3 - Theoretical
Genetic damage, effects
Week 3 - Practice
Selection of genetic testing and study design
Week 4 - Theoretical
DNA damage repair, and genetic risk assessment process
Week 4 - Practice
Selection of genetic testing and study design
Week 5 - Theoretical
Pharmacogenetics domains
Week 5 - Practice
Genetic risk assessment methods
Week 6 - Theoretical
Change due to drug interactions and genetics
Week 6 - Practice
Genetic risk assessment methods
Week 7 - Theoretical
Article discussion
Week 7 - Practice
Paper presentation
Week 8 - Theoretical & Practice
(Midterm exam) Paper presentation
Week 9 - Theoretical
Genetic difference in impact on drug interactions - or inhibition of enzyme induction
Week 9 - Practice
Impact of pharmacogenetics in the treatment of drug tests
Week 10 - Theoretical
Pharmacodynamics of drugs that changes the genetic difference
Week 10 - Practice
Examination of the application fields of pharmacogenetic tests
Week 11 - Theoretical
Examination of drug and enzyme polymorphism
Week 11 - Practice
Phenotypic methods applications
Week 12 - Theoretical
Examination of drug and enzyme polymorphism
Week 12 - Practice
Probe drug applications
Week 13 - Theoretical
Clinical use of pharmacogenomics studies
Week 13 - Practice
Pharmacogenetic applications of molecular cytogenetic testing
Week 14 - Theoretical
Clinical use of pharmacogenomics studies
Week 14 - Practice
Pharmacogenetic applications of molecular genetic testing
Week 15 - Final Exam
Final exam
Assessment Methods and Criteria
Type of AssessmentCountPercent
Presentation1%5
Verbal Examination1%5
Midterm Examination1%20
Final Examination1%70
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory144170
Lecture - Practice143156
Midterm Examination1718
Final Examination111112
TOTAL WORKLOAD (hours)146
Contribution of Learning Outcomes to Programme Outcomes
PÇ-1
PÇ-2
PÇ-3
PÇ-4
PÇ-5
PÇ-6
PÇ-7
PÇ-8
PÇ-9
PÇ-10
PÇ-11
PÇ-12
PÇ-13
PÇ-14
PÇ-15
PÇ-16
OÇ-1
5
OÇ-2
5
5
OÇ-3
5
5
5
OÇ-4
4
3
4
5
5
5
4
4
5
OÇ-5
5
4
5
5
Adnan Menderes University - Information Package / Course Catalogue
2026