
| Course Code | : BİS626 |
| Course Type | : Area Elective |
| Couse Group | : Third Cycle (Doctorate Degree) |
| Education Language | : Turkish |
| Work Placement | : N/A |
| Theory | : 3 |
| Prt. | : 0 |
| Credit | : 3 |
| Lab | : 0 |
| ECTS | : 3 |
To introduce the topics in probability and statistics useful in computational molecular biology and bioinformatics.
Brief history of Bioinformatics, Basic concepts of Molecular Biology, Markov Chain, The Analysis of one DNA sequence, Modeling DNA and signals in DNA, Alignments and simple tests for significant similarity in an Alignment(BLAST technique), Alignment algorithms for two sequences and dynamic programming, Entropy and related concepts, Relative entropy and binding energy, Finding instances of known and unknown Sites, Correlation of positions in sequences, Gene expression, microarrays, and multiple testing, Evolutionary models/ Phylogenetic tree estimation.
| 1. | Be able to identify topics in probability and statistics used in computational biology and bioinformatics |
| 2. | Be able to explain and interpret selected statistical models used in bioinformatics. |
| 3. | Be able to relate the topics in probability and statistics to bioinformatics computer packages |
| 4. | Be able to develop statistical techniques useful for analyzing data in the field of computational biology |
| 5. | To provide approaches to the analysis of large amounts of data in data banks |
| Type of Assessment | Count | Percent |
|---|---|---|
| Attending Lectures | 1 | %5 |
| Assignment | 1 | %5 |
| Midterm Examination | 1 | %20 |
| Final Examination | 1 | %70 |
| Activities | Count | Preparation | Time | Total Work Load (hours) |
|---|---|---|---|---|
| Lecture - Theory | 14 | 0 | 3 | 42 |
| Midterm Examination | 1 | 10 | 1 | 11 |
| Final Examination | 1 | 20 | 1 | 21 |
| TOTAL WORKLOAD (hours) | 74 | |||
PÇ-1 | PÇ-2 | PÇ-3 | PÇ-4 | PÇ-5 | PÇ-6 | PÇ-7 | |
OÇ-1 | 4 | 5 | 5 | 4 | 3 | 2 | 3 |
OÇ-2 | 5 | 4 | 5 | 5 | 3 | 2 | 2 |
OÇ-3 | 4 | 4 | 4 | 4 | 3 | 3 | 3 |
OÇ-4 | 5 | 5 | 5 | 4 | 3 | 4 | 4 |
OÇ-5 | |||||||