
| Course Code | : BYK608 |
| Course Type | : Required |
| Couse Group | : Third Cycle (Doctorate Degree) |
| Education Language | : Turkish |
| Work Placement | : N/A |
| Theory | : 2 |
| Prt. | : 2 |
| Credit | : 3 |
| Lab | : 0 |
| ECTS | : 5 |
The aim of this course is to give the students the understanding of free radical types and radicalic reactions in biological systems, to give the students an understanding of oxidative damage which is one of the most emphasized subjects of science by giving basic information about free radicals
Normal metabolic function or examination of free radicals generated under stress conditions and effects of free radicals on cell signaling and gene expression. Relationships of oxidant and antioxidant. Free radical scavengers against the destructive effects of free radicals and antioxidants, Oxidative damage in connection with pathogenesis of aging and disease.
| 1. | To understand the effects of oxidative damage on lipids, DNA and proteins |
| 2. | Literature review and interpretation of free radicals |
| 3. | To learn the types of free radicals |
| 4. | To be able to understand and use conventional biochemical techniques used in the determination of free radicals |
| 5. | To understand the mechanisms of action of free radicals |
| 1. | Oxidative stress: oxidants and antioxidants Helmunt Sies |
| 2. | Cellular antioxidant defense mechanisms Ching Kuang Chow |
| 3. | B.Hallwell, J.M.C. Gutterdge, “Free Radicals in Biology and Medicine”, fourth edition,Oxford Science Publications, 2007 |
| Type of Assessment | Count | Percent |
|---|---|---|
| Midterm Examination | 1 | %40 |
| Final Examination | 1 | %60 |
| Activities | Count | Preparation | Time | Total Work Load (hours) |
|---|---|---|---|---|
| Lecture - Theory | 14 | 4 | 2 | 84 |
| Midterm Examination | 1 | 18 | 2 | 20 |
| Final Examination | 1 | 19 | 2 | 21 |
| TOTAL WORKLOAD (hours) | 125 | |||
PÇ-1 | PÇ-2 | PÇ-3 | PÇ-4 | PÇ-5 | |
OÇ-1 | 5 | 4 | 5 | 4 | 5 |
OÇ-2 | 5 | 4 | 5 | 5 | 4 |
OÇ-3 | 5 | 5 | 5 | 4 | 5 |
OÇ-4 | 5 | 4 | 4 | 5 | 5 |
OÇ-5 | 5 | 4 | 5 | 4 | 5 |