Information Package / Course Catalogue
Advanced Biochemistry
Course Code: BYK620
Course Type: Required
Couse Group: Third Cycle (Doctorate Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 3
Prt.: 0
Credit: 3
Lab: 0
ECTS: 5
Objectives of the Course

To provide a broad-based background in laboratory science by drawing attention to the latest techniques in biochemistry.

Course Content

Amino acids and peptides - Structure and function of proteins- Clarification of protein structure- Myoglobin and hemoglobin - Connective tissue proteins - General properties of enzymes - Enzyme kinetics - Regulation of enzyme activity - Carbohydrate and Lipid Metabolism - Classification of carbohydrates - the digestion and absorption of carbohydrates - Glycolysis - Citric acid cycle - Oxidative forsorilasyon - Gluconeogenesis - The pentose phosphate pathway - Glycogen Metabolism - Classification of lipids - Fatty acid synthesis and oxidation - Classification of Steroids-lipids digestion, absorption and transport - Lipoproteins and lipoprotein metabolism disorders- Amino acid metabolism and protein synthesis - the digestion and absorption of proteins - Amino acid degradation and urea cycle- Catabolism of the carbon skeletons of amino acids - Porphyrins and bile pigments - the metabolism of purine and pyrimidine nucleotides - genetic information - DNA structure - replication and repair - Gene regulation - Recombination - RNA Synthesis - Protein synthesis - Gene expression control - Hormones - Vitamins - Trace Elements and Nutrition- The mechanism of action of hormones - Thyroid and parathyroid hormones - Androgens - Estrogens and progesterone - The adrenal gland hormones - Pancreatic hormones - Fat-soluble vitamins - Water-soluble vitamins - Trace elements - Basic principles of nutrition.

Name of Lecturer(s)
Learning Outcomes
1.To be able to read the scientific literature and interpret the information about biomolecular structure and function
2.To discuss the relationship between biomolecular structure and function
3.Being able to cooperate as a team employee and improve herself/himself by following the innovations in science(
4.To be able to understand the combination of structural and functional properties of amino acids, proteins, carbohydrates, nucleotides, lipids and membranes
5.To be able to use modern library search and information methods to obtain information about the structure and function of biomolecules
Recommended or Required Reading
1.Biochemistry by lehninger
2.Biochemistry :Mary K. Campbell
3. Keshav Trehan Biyokimya
Weekly Detailed Course Contents
Week 1 - Theoretical
The role of water in cell biology
Week 2 - Theoretical
Molecular structures and reasoning at atomic level in biology. Historical overview
Week 3 - Theoretical
Biological macromolecules, three-dimensional conformation, weak interactions and their importance in life, biological macromolecules in hydrophobic and hydrophilic environments, symmetry, macromolecules and structures
Week 4 - Theoretical
Protein design, sequence, secondary structure, super secondary structures, structural centers, tertiary structure, protein-protein relationship
Week 5 - Theoretical
Protein folding & protein stability
Week 6 - Theoretical
Enzymes: 3D structures and activities
Week 7 - Theoretical
Membrane proteins, hydrophobicity and protein-lipid interactions, Energy & Signal transmission- Molecular machines, Atomic level selected model systems (high resolution structures and bacteriododsin, rhodopsin to determine the possible functions)
Week 8 - Intermediate Exam
Advanced Biochemistry Midterm Exam
Week 9 - Theoretical
Structural proteins, collagen, super helixes, silk, amyloids, amyloidosis, biopolymers / biomaterials
Week 10 - Theoretical
Nucleic acids: structure & function
Week 11 - Theoretical
DNA-binding proteins, protein-DNA recognition in eukaryotic and prokaryotic organisms
Week 12 - Theoretical
Protein-DNA interactions Supercatated DNA, Nucleosome structure
Week 13 - Theoretical
Carbohydrates: structure & function
Week 14 - Theoretical
Polysaccharides (Chitin, Cellulose) & two-phase protein-polysaccharide complex systems
Week 15 - Theoretical
Lipid chemistry and biological membranes
Week 16 - Final Exam
Advanced Biochemistry Final Exam
Assessment Methods and Criteria
Type of AssessmentCountPercent
Midterm Examination1%40
Final Examination1%60
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory144284
Midterm Examination118220
Final Examination119221
TOTAL WORKLOAD (hours)125
Contribution of Learning Outcomes to Programme Outcomes
PÇ-1
PÇ-2
PÇ-3
PÇ-4
PÇ-5
OÇ-1
5
4
5
4
5
OÇ-2
5
5
4
5
4
OÇ-3
5
4
5
5
4
OÇ-4
5
4
5
4
5
OÇ-5
5
5
4
5
4
Adnan Menderes University - Information Package / Course Catalogue
2026