Information Package / Course Catalogue
Regenerative Tissue Engineering
Course Code: BYK625
Course Type: Area Elective
Couse Group: Third Cycle (Doctorate Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 3
Prt.: 0
Credit: 3
Lab: 0
ECTS: 3
Objectives of the Course

To teach the basic concepts of cell and tissue engineering, especially by emphasizing the interaction of cells with each other and their environment.

Course Content

The concept of tissue engineering, biomaterials and propertiesi, the importance of different structural skeletons in tissue engineering, regenerative medicine and application areas of regenerative medicine, the use of stem cells in regeneration of bone and cartilage tissues, bone and cartilage cell production in artificial tissue enviroments and comparison to other methods of cell culture (eg, a single layer, pellets, 3D culture method, etc.).

Name of Lecturer(s)
Learning Outcomes
1.To teach basic definitions and concepts in cell and tissue engineering, stem cell, biodegradable scaffold and cell-biomaterial interactions
2.Examination of the basic components of tissue engineering, selection, production and evaluation methods of these components and their potential clinical applications
3.To gain the ability of researching, analyzing, comparing and criticizing the existing methods and proposing alternative solutions.
4.To be able to distinguish the interdisciplinary characteristics of clinical and research methods and examination of successful working examples between medical doctors, basic scientists and engineers
5.Discussion of ethical values ??in tissue engineering with examples
Recommended or Required Reading
1.Fundamentals of Tissue Engineering and Regenerative Medicine: Ulrich Meyer,Jörg Handschel,Hans Peter Wiesmann
2.Tissue Engineering in Regenerative Medicine: Harold S. Bernstein
Weekly Detailed Course Contents
Week 1 - Theoretical
Brief history and current position of tissue engineering course
Week 2 - Theoretical
Introduction to basic cell and tissue biology and concepts
Week 3 - Theoretical
Examples of tissue engineering from nature: Embryogenesis and development
Week 4 - Theoretical
Embryonic and adult stem cells
Week 5 - Theoretical
Remodeling and wound healing
Week 6 - Theoretical
Tissue regeneration
Week 7 - Theoretical
Tissue scaffolding, material selection, production and properties
Week 8 - Intermediate Exam
Regenerative Tissue Engineering Midterm Exam
Week 9 - Theoretical
Factors controlling cell and tissue growth and differentiation; Growth factors, Extracellular matrix
Week 10 - Theoretical
Intercellular interaction; Receptor / ligand interactions Cell-biomaterial interactions
Week 11 - Theoretical
Cellular mechanics
Week 12 - Theoretical
Gene expression in cells
Week 13 - Theoretical
Bioreactor design and advanced devices
Week 14 - Theoretical
Tissue engineering applications: - Bone, cartilage, vascular grafts - Heart, liver, nerve regeneration
Week 15 - Theoretical
Biological, physical and chemical limitations of tissue engineering systems
Week 16 - Final Exam
Regenerative Tissue Engineering Final Exam
Assessment Methods and Criteria
Type of AssessmentCountPercent
Midterm Examination1%40
Final Examination1%60
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory141242
Midterm Examination114216
Final Examination115217
TOTAL WORKLOAD (hours)75
Contribution of Learning Outcomes to Programme Outcomes
PÇ-1
PÇ-2
PÇ-3
PÇ-4
PÇ-5
OÇ-1
5
4
5
4
5
OÇ-2
5
5
4
4
5
OÇ-3
5
5
5
4
5
OÇ-4
5
4
5
4
5
OÇ-5
5
5
4
5
4
Adnan Menderes University - Information Package / Course Catalogue
2026