Information Package / Course Catalogue - Adnan Menderes University

General Information Unit Staff Academic Information Programme Outcomes Course Structure Diagram Contact Information

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Lipid and Membrane Biochemistry

Course Code	: BYK626
Course Type	: Required
Couse Group	: Third Cycle (Doctorate Degree)
Education Language	: Turkish
Work Placement	: N/A

Theory	: 3
Prt.	: 0
Credit	: 3
Lab	: 0
ECTS	: 5

Objectives of the Course

The aim of this course is to give the basic knowledge about the structure and function of lipids and biological membranes.

Course Content

Lipids, fatty acids, triacylglycerols, phosphoacylglycerols, soaps, Sphingolipids, glycolipids, steroids, cholesterol, Biological Membranes and Membrane Receptors, fluid Mosaic membrane Model and Transport

Name of Lecturer(s)

Learning Outcomes

1.	To understand and compare the chemical composition of membranes
2.	To understand the basic processes of membrane biogenesis
3.	To understand the membrane dynamics in the cell
4.	To be able to comprehend and compare the types and characteristics of membrane proteins in the cell membrane
5.	To be able to explain the different ways of transporting solutes and water through membranes

Recommended or Required Reading

1.	Biochemistry of Lipids, Lipoproteins and Membranes:J.E. Vance,Dennis E. Vance
2.	Lipid Biochemistry: An Introduction :Michael I. Gurr,John L. Harwood,Keith N. Frayn

Weekly Detailed Course Contents

Week 1 - Theoretical

Introduction to biological membranes, basics of membrane structure

Week 2 - Theoretical

Lipid components of membranes; classification and chemical properties of lipids, lipid composition, monolayer, bilayer, micelles, liposomes and biomembranes

Week 3 - Theoretical

Protein components of membranes; type, structure, arrangement and properties of membrane proteins

Week 4 - Theoretical

Hydropathy curves and prediction of secondary structure, folding of membrane proteins

Week 5 - Theoretical

Dynamics of membrane proteins, rotational and translational diffusion, measurement techniques

Week 6 - Theoretical

Protein-lipid interactions and membrane function

Week 7 - Theoretical

Transport from membranes, electron transport management systems, carriers, channels

Week 8 - Intermediate Exam

Lipid and Membrane Biochemistry Midterm Exam

Week 9 - Theoretical

H + transport by mitochondrial respiration chain, chemiozmotic theory, proton transport with complexes

Week 10 - Theoretical

Light-mediated H + transport, H + transport in tilacoids, bacterial photosynthetic reaction center, bacteriododsin

Week 11 - Theoretical

F-, V-, P-type ATPases and ATP synthesis, structure and molecular mechanism of F-type ATPases

Week 12 - Theoretical

Primary ion pumps and ionic gradient formation, structure and function of P-type ATPases, ABC-transporters

Week 13 - Theoretical

Carrier transport, molecular mechanism

Week 14 - Theoretical

Biological overview of channel functions, ion channels, ion-carrying and ion-forming channels

Week 15 - Theoretical

Ligand gated and voltage gated channels, water channels, aquaforins and types

Week 16 - Final Exam

Lipid and Membrane Biochemistry Final Exam

Assessment Methods and Criteria

Type of Assessment	Count	Percent
Midterm Examination	1	%40
Final Examination	1	%60

Workload Calculation

Activities	Count	Preparation	Time	Total Work Load (hours)
Lecture - Theory	14	4	2	84
Midterm Examination	1	18	2	20
Final Examination	1	19	2	21
TOTAL WORKLOAD (hours)				125

Contribution of Learning Outcomes to Programme Outcomes

	PÇ-1	PÇ-2	PÇ-3	PÇ-4	PÇ-5
OÇ-1	5	4	5	4	5
OÇ-2	5	5	4	5	5
OÇ-3	5	4	4	5	5
OÇ-4	5	4	5	5	4
OÇ-5	5	5	4	4	5

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