Information Package / Course Catalogue
Biomarkers
Course Code: BYK628
Course Type: Area Elective
Couse Group: Third Cycle (Doctorate Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 3
Prt.: 0
Credit: 3
Lab: 0
ECTS: 5
Objectives of the Course

The Basic Purpose of this course is learning types of biomarkers.

Course Content

Definition and classification of biomarkers, biomarkers associated with physiological and pathological conditions, the detection methods of biomarkers in body fluids and tissues, Role of proteomics in biomarker determination studies.

Name of Lecturer(s)
Learning Outcomes
1.To have knowledge about the basic mechanisms of histochemistry and immunohistochemistry
2.Learning the basic immunohistochemical and molecular markers
3.To learn how platform analyses of selected biomarkers are dependent on proper choice of method and proper sample preparation
4.To learn underlying principles in quantification of biomarkers in central techniques designed on subcellular fractions
5.To have knowledge about novel biomarkers and the biomarkers currently in use
Recommended or Required Reading
1.Basic Pathology, Robbins and Cortran. (2008).
2.Ackerman Pathology, Rosai, (2009), Surgical Pathology
Weekly Detailed Course Contents
Week 1 - Theoretical
What is the histochemistry
Week 2 - Theoretical
The mechanisms of immunhistochemistry
Week 3 - Theoretical
Histochemical markers which are basically used
Week 4 - Theoretical
İmmunhistochemical markers which are basically used.
Week 5 - Theoretical
Molecular markers
Week 6 - Theoretical
Basic molecular pathology
Week 7 - Theoretical
Biomarkers heterogeneity: what to measure depends on the stability of the sample, resolution of method and preparation of the sample.
Week 8 - Intermediate Exam
Biomarkers Midterm Exam
Week 9 - Theoretical
Understanding the underlying principles of antibody-based analyses
Week 10 - Theoretical
Understanding the underlying principles of nucleic acid-based techniques
Week 11 - Theoretical
Understanding the underlying principles of mass-spectrometry analyses
Week 12 - Theoretical
Critical selection of Method
Week 13 - Theoretical
Critical view on reference range
Week 14 - Theoretical
Novel biomarkers
Week 15 - Theoretical
Therapy biomarkers
Week 16 - Final Exam
Biomarkers Final Exam
Assessment Methods and Criteria
Type of AssessmentCountPercent
Midterm Examination1%40
Final Examination1%60
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory144284
Midterm Examination118220
Final Examination119221
TOTAL WORKLOAD (hours)125
Contribution of Learning Outcomes to Programme Outcomes
PÇ-1
PÇ-2
PÇ-3
PÇ-4
PÇ-5
OÇ-1
5
4
5
4
5
OÇ-2
5
4
4
5
4
OÇ-3
5
5
5
4
5
OÇ-4
5
4
5
5
4
OÇ-5
5
5
4
5
5
Adnan Menderes University - Information Package / Course Catalogue
2026