Information Package / Course Catalogue
Genotoxicology
Course Code: BİO632
Course Type: Area Elective
Couse Group: Third Cycle (Doctorate Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 2
Prt.: 0
Credit: 2
Lab: 0
ECTS: 8
Objectives of the Course

Genotoxicity, mutagenicity and carcinogenicity with the concepts and their implications, to teach methods of detection.

Course Content

Genotoxicity, mutagenicity and carcinogenicity concepts and their effects, methods of detection

Name of Lecturer(s)
Learning Outcomes
1.Learning genetic toxicology
2.Learning the environmental impact of genotoxin learning
3.Learning genotoxic in vitro test methods
4.Learning biotechnological applications in genotoxicology
5.Learning to be identified genetic risk
Recommended or Required Reading
1.R.Marcos, B.Kaya (2001). Course on genetic toxicology, kurs notları, Akdeniz Üniv. Fen-edeb. Fak. Biyoloji Böl.
2. Waters.D.M. Genetic toxicology of complex mixtures. Plenum Press, 1990
3.Grover, L.P. Chemical Carcinogens and DNA. CRC. Press, 1979
Weekly Detailed Course Contents
Week 1 - Theoretical
Introduction to genotoxicology
Week 2 - Theoretical
Genotoxic agents
Week 3 - Theoretical
Environmental effects of genotoxin (eco-genotoxicology)
Week 4 - Theoretical
Causes cellular DNA damage
Week 5 - Theoretical
DNA repair
Week 6 - Theoretical
Examination of oxidative DNA damage
Week 7 - Theoretical
in vitro genotoxic test materials
Week 8 - Theoretical
Measurement of reversible Genotoxic effects in vivo (Midterm exam)
Week 9 - Theoretical
Affects the level of chromosomal
Week 10 - Theoretical
Affects the level of genes
Week 11 - Theoretical
Biotechnological applications in Genotoxicology
Week 12 - Theoretical
Genotoxicology studies in the use of the comet assay
Week 13 - Theoretical
Genetic toxicology goals, determination of genetic risks
Week 14 - Theoretical
In silico approaches to determine genotoxic effect
Assessment Methods and Criteria
Type of AssessmentCountPercent
Midterm Examination1%30
Final Examination1%70
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory1462112
Assignment105050
Midterm Examination115116
Final Examination115116
TOTAL WORKLOAD (hours)194
Contribution of Learning Outcomes to Programme Outcomes
PÇ-1
PÇ-2
PÇ-3
PÇ-4
PÇ-5
PÇ-6
PÇ-7
PÇ-8
PÇ-9
PÇ-10
PÇ-11
PÇ-12
PÇ-13
PÇ-14
OÇ-1
3
3
2
3
3
OÇ-2
3
4
3
4
3
OÇ-3
4
3
3
3
4
OÇ-4
3
3
3
3
OÇ-5
3
4
4
3
3
Adnan Menderes University - Information Package / Course Catalogue
2026