Information Package / Course Catalogue - Adnan Menderes University

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Apoptosis and It’s Role On Development

Course Code	: BİO626
Course Type	: Area Elective
Couse Group	: Third Cycle (Doctorate Degree)
Education Language	: Turkish
Work Placement	: N/A

Theory	: 3
Prt.	: 0
Credit	: 3
Lab	: 0
ECTS	: 8

Objectives of the Course

It aims to give information about mechanism, the role on improvement and importance of apoptosis.

Course Content

Cell death, cell death types, apoptosis, necrosis, the differences between apoptosis and necrosis,the mechanism of apoptosis, the role of apoptosis in development.

Name of Lecturer(s)

Learning Outcomes

1.	Learn about the functioning and importance of apoptosis.
2.	Knows and explains the mechanisms of apoptosis.
3.	Distinguishes between healthy and apoptotic cells.
4.	Understands the importance of apoptosis in embryogenesis.
5.	Relates to original lessons based on the cell.
6.	Follows the sources related to the subject and interprets the current information.

Recommended or Required Reading

1.	-Jacobson, Mike., McCarthy, Nicola: Apoptosis methods in pharmacology and toxicology : approaches to measurement and quantification: / edited by Myrtle A. Davis.ISSN 01996385000 , 2002

Weekly Detailed Course Contents

Week 1 - Theoretical

What is apoptosis? Why is it important ? How is it controlled? What is it’s importance in embryology?

Week 2 - Theoretical

Cell types that we can see apoptosis, modulators of apoptosis, induct,on of apoptosis, the role of mitokondri in apoptosis

Week 3 - Theoretical

The steps, mechanism of apoptosis , definition of necrosis.

Week 4 - Theoretical

Cell types that we can see apoptosis,

Week 5 - Theoretical

Biochemical properties of apoptosis, physiological significance.

Week 6 - Theoretical

Biochemical characteristics of apoptosis, physiological importance of it, receptor characteristics of apud cells-Contuniation

Week 7 - Theoretical

Connection between apoptosis and improvement of nerve system.

Week 8 - Theoretical

Connection between apoptosis and improvement of nerve system (Midterm)

Week 9 - Theoretical

Methods for determining apoptotic cells

Week 10 - Theoretical

Methods for determining apoptotic cells -Contuniation

Week 11 - Theoretical

Methods for determining apoptotic cells; TUNEL and other methods.

Week 12 - Theoretical

Methods for determining apoptotic cells; TUNEL and other methods.

Week 13 - Theoretical

Connection between apoptotic mechanisms and cancer, otoimmun, neurodegenerative diseases.

Week 14 - Theoretical

Connection between apoptotic mechanisms and cancer, otoimmun, neurodegenerative diseases.

Assessment Methods and Criteria

Type of Assessment	Count	Percent
Midterm Examination	1	%30
Final Examination	1	%70

Workload Calculation

Activities	Count	Preparation	Time	Total Work Load (hours)
Lecture - Theory	14	2	3	70
Assignment	2	6	6	24
Reading	14	4	3	98
Midterm Examination	1	2	1	3
Final Examination	1	2	1	3
TOTAL WORKLOAD (hours)				198

Contribution of Learning Outcomes to Programme Outcomes

	PÇ-1	PÇ-2	PÇ-3	PÇ-4	PÇ-5	PÇ-6	PÇ-7	PÇ-8	PÇ-9	PÇ-10	PÇ-11	PÇ-12	PÇ-13	PÇ-14
OÇ-1	3	4	4	4			5	5	5				4
OÇ-2	5	4	4	5	4		5	5	5				5	4
OÇ-3	3	3	4	4	3		5	5	5				4	4
OÇ-4	4	5	4	4	4		5	4	4				4	4
OÇ-5	4	4	4	5	5		4	5	4					4
OÇ-6													5

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