Information Package / Course Catalogue
Chemical Mutagenesis
Course Code: BİO631
Course Type: Area Elective
Couse Group: Third Cycle (Doctorate Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 3
Prt.: 0
Credit: 3
Lab: 0
ECTS: 8
Objectives of the Course

To give information about research of mutations, methods of mutagenesis tests, the comutagens and antimutagens

Course Content

Methods of mutagenesis tests, comutagens and antimutagens.

Name of Lecturer(s)
Learning Outcomes
1.1. To obtain information about mutations and the history of mutation researches.
2.2. Mutagenicity test methods provide basic information about the acquisition of
3.3. To provide the acquisition of basic information about mutagenicity testing methods.
4.4. To learn methods of in vitro, human and mammalian cell culture techniques .
5.5. Learning about chemical mutagens
6.6. To give information about the determinants of mutagenic effect and determinants of structure-activity.
7.7. Learning of komutagens andantimutagens.
Recommended or Required Reading
1.Leitão, J.M. . Chemical Mutagenesis. BioFIG, FCT, Universidade do Algarve, 8005-139 Campus de Gambelas, Faro, Portugal
2.Lecturer notes
Weekly Detailed Course Contents
Week 1 - Theoretical
The hisory and duty of mutation searches
Week 2 - Theoretical
Preventation of mutations and their repairing system
Week 3 - Theoretical
Methods of mutagenity tests, dominant-letal test
Week 4 - Theoretical
Intraanimal culture of micoorganisms
Week 5 - Theoretical
In vivo observations, Drosophila, Fanerogams
Week 6 - Theoretical
In vivo observations, Fanerogams
Week 7 - Theoretical
In vitro methods, human and mammalian cell cultures
Week 8 - Theoretical
Test methods in low eucaryotic and procaryotic organisms
Week 9 - Theoretical
Chemical mutagens, forming radicals
Week 10 - Theoretical
Nucleic asit antimetabolites, metals and metal organic compounds
Week 11 - Theoretical
The indicators of mutagenic effects: structure-effect relationship, the difference of sensitivity
Week 12 - Theoretical
Comutagens
Week 13 - Theoretical
Antimutagens
Week 14 - Theoretical
Antimutagens
Assessment Methods and Criteria
Type of AssessmentCountPercent
Midterm Examination1%30
Final Examination1%70
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory1453112
Assignment54020
Term Project120020
Reading143042
Midterm Examination1516
Final Examination1516
TOTAL WORKLOAD (hours)206
Contribution of Learning Outcomes to Programme Outcomes
PÇ-1
PÇ-2
PÇ-3
PÇ-4
PÇ-5
PÇ-6
PÇ-7
PÇ-8
PÇ-9
PÇ-10
PÇ-11
PÇ-12
PÇ-13
PÇ-14
OÇ-1
3
3
3
4
OÇ-2
3
4
4
3
OÇ-3
3
3
3
3
4
OÇ-4
3
4
3
3
OÇ-5
4
3
3
3
4
OÇ-6
3
3
3
3
3
OÇ-7
3
3
3
3
Adnan Menderes University - Information Package / Course Catalogue
2026