Information Package / Course Catalogue
Bioinformatic Programs and Applications in Recombinant Technology
Course Code: MBTK643
Course Type: Area Elective
Couse Group: Third Cycle (Doctorate Degree)
Education Language: English
Work Placement: N/A
Theory: 3
Prt.: 0
Credit: 3
Lab: 0
ECTS: 10
Objectives of the Course

The aim of this course help the students to learn the fundamentals of nucleic acid and protein sequence analysis and the analysis of complex biological systems using bioinformatic tools

Course Content

The subject is Genomics, GenBank Sequence Database, Sequence Alignment, Gen Prediction and realated Programe (NCBI's Entrez, BLAST, PSI-BLAST, ClustalW, Pfam, BIOEDIT, GENEMARKER, SEQUIN, CAP3, ORF Finder, GENSCAN, MICROSATELLITE REPEATS FINDER)

Name of Lecturer(s)
Learning Outcomes
1.By the end of the course the students learn the basic concepts behind Bioinformatics and Computational Biology tools
2.Students will be able to define sequence analysis methods
3.Students will be able to state different application areas of sequence analysis
4.Students have knowledge about the details and area of usage of the most commonly used bioinformatic tools
5.Students have experience to use most important bioinformatic tools
6.Students will be able to interpret the results of sequence analysis methods
Recommended or Required Reading
1.Bioinformatics, A practical Guide to the Analysis of Genes and proteins, A.D. Baxevanis ve B.F.F. Ouellette, 1998, ISBN0-471-19196-5
Weekly Detailed Course Contents
Week 1 - Theoretical
Introduction to bioinformatics
Week 2 - Theoretical
GenBank and BLAST Verbal lecture
Week 3 - Theoretical
BLAST practice
Week 4 - Theoretical
Comparison of two or more DNA / protein sequences/ combining: alingment/CAP
Week 5 - Theoretical
Comparison of two or more DNA / protein sequences/ combining: alingment/CAP
Week 6 - Theoretical
Primer design
Week 7 - Theoretical
Data entry into GenBank database-I
Week 8 - Theoretical
Data entry into GenBank database-II (Midterm exam)
Week 9 - Theoretical
Phylogenetic tree construction
Week 10 - Theoretical
Determination of microsatellite locus lengths
Week 11 - Theoretical
Microsatellite data entry
Week 12 - Theoretical
Population genetics applications (Microchecker, DNAsp, Popgene, Genepop)
Week 13 - Theoretical
Population genetics applications (Arlequin, Populations, Phylip)
Week 14 - Theoretical
Population genetics applications (Bottleneck, Migrate, Structure)
Assessment Methods and Criteria
Type of AssessmentCountPercent
Presentation1%5
Assignment1%5
Midterm Examination1%20
Final Examination1%70
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory144398
Assignment118220
Presentation 120222
Individual Work130565
Midterm Examination118220
Final Examination123225
TOTAL WORKLOAD (hours)250
Contribution of Learning Outcomes to Programme Outcomes
PÇ-1
PÇ-2
PÇ-3
PÇ-4
PÇ-5
PÇ-6
PÇ-7
PÇ-8
PÇ-9
PÇ-10
PÇ-11
PÇ-12
PÇ-13
OÇ-1
5
5
3
5
5
3
4
4
4
4
3
3
5
OÇ-2
5
5
3
5
5
3
4
4
4
4
3
3
5
OÇ-3
5
5
3
4
4
3
5
5
5
5
3
3
5
OÇ-4
5
5
3
4
4
3
5
5
5
5
3
3
5
OÇ-5
5
5
3
4
4
3
5
5
5
5
3
3
5
OÇ-6
5
5
3
4
4
3
5
5
5
5
3
3
5
Adnan Menderes University - Information Package / Course Catalogue
2026