
| Course Code | : ONK603 |
| Course Type | : Required |
| Couse Group | : Third Cycle (Doctorate Degree) |
| Education Language | : Turkish |
| Work Placement | : N/A |
| Theory | : 2 |
| Prt. | : 2 |
| Credit | : 3 |
| Lab | : 0 |
| ECTS | : 4 |
It is aimed to explain the signal transmission mechanisms in cancer cells in detail.
Receptor types and activation mechanisms - Signal transduction via tyrosine kinase growth factor receptor - Signal transmission in cell death - The role of PI3 Kinases in cell signal transmission
| 1. | Can express signal transmission in cancer molecular biology in general terms |
| 2. | Recognize and understand cancer signal transmission systems and molecular targets, molecular mechanisms of control of transcriptional regulators |
| 3. | Understand the signal mechanisms of common cancers with examples |
| 4. | Comprehend the signaling changes in cancer cell division and life |
| 5. | Can analyze and plan studies on cancer cell signaling mechanisms |
| 1. | Diagnostic Approach to Clinical Oncology Mario W. Fiorentino PICCIN 1999 |
| 2. | Molecular Biology in Cancer Medicine. Razelle Kurzrock, Moshe Talpaz, Martin Dunitz 1995. |
| 3. | AJCC Cancer Staging Handbook.Irvin D. Fleming. Lippincott Willams & Wilkins 1998 |
| 4. | Manual of Clinical Oncology. D.K. Hossfeld, C.D. Sherman, R.R. Love, F.X. Bosch Springer- Verlag, 1990 Fith Edition. |
| 5. | Pathologic Basis of Disease. Vinay Kumar, Abul K. Abbas, Nelson Fausto, Elsevier Saunderss, 2005 Seventh Edition |
| 6. | Molecular Mechanism of Cancer. Georg F. Weber, Springer 2007 |
| 7. | The Biology of Cancer Robert A. Weinberg, Gariand Science 2007 |
| 8. | Cancer Principles and Practice of Oncology Devita VT, Lawrence TS, Rosenberg SA, Wolters Kluwer& Lippincott Willams & Wilkins 2008 Eighth Edition. |
| Type of Assessment | Count | Percent |
|---|---|---|
| Assignment | 1 | %5 |
| Quiz | 1 | %5 |
| Midterm Examination | 1 | %20 |
| Final Examination | 1 | %70 |
| Activities | Count | Preparation | Time | Total Work Load (hours) |
|---|---|---|---|---|
| Lecture - Theory | 14 | 0 | 2 | 28 |
| Lecture - Practice | 14 | 0 | 2 | 28 |
| Assignment | 2 | 4 | 0 | 8 |
| Quiz | 1 | 0 | 1 | 1 |
| Midterm Examination | 1 | 4 | 2 | 6 |
| Final Examination | 1 | 24 | 2 | 26 |
| TOTAL WORKLOAD (hours) | 97 | |||
PÇ-1 | PÇ-2 | PÇ-3 | PÇ-4 | PÇ-5 | PÇ-6 | PÇ-7 | PÇ-8 | PÇ-9 | PÇ-10 | PÇ-11 | PÇ-12 | PÇ-13 | PÇ-14 | PÇ-15 | |
OÇ-1 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 4 | 4 | 5 | 5 | 5 | 5 | 5 | 5 |
OÇ-2 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 4 | 4 | 5 | 5 |
OÇ-3 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 |
OÇ-4 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 4 | 5 | 5 | 5 | 5 |
OÇ-5 | 5 | 5 | 5 | 4 | 4 | 4 | 4 | 5 | 5 | 5 | 5 | 4 | 5 | 5 | 5 |