Information Package / Course Catalogue
Basic Approach to Oncology
Course Code: ONK605
Course Type: Required
Couse Group: Third Cycle (Doctorate Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 2
Prt.: 2
Credit: 3
Lab: 0
ECTS: 4
Objectives of the Course

To define basic oncology concepts, to understand the molecular basis of carcinogenesis and anticancer therapy with examples.

Course Content

The aim of this course is to understand the relationship between carcinogenesis, cell cycle and cancer, differentiation, its role in transformation and cancer development and its molecular mechanisms. Cell death mechanisms, angiogenesis, invasion and metastasis, signal pathways in cancer, the importance of oncogene and tumor suppressor genes in cancer diagnosis, treatment and follow-up. In practice courses, cancer cell culture, Western Blot application, DNA from tumor tissue, RNA isolation, and real time PCR mutation analysis in cancer diagnosis will be discussed.

Name of Lecturer(s)
Learning Outcomes
1.To learn the basic oncological approach
2.To examine the carcinogenesis-tumogenesis steps
3.To discuss genetic changes and mutations in cancer.
4.Review of cancer-host and immune system relationships
5.To discuss anticancer treatment differences
Recommended or Required Reading
1.A beginner’s guide to targeted cancer treatments / by Elaine Vickers. (Elaine Ruth), author. Hoboken, NJ : Wiley, 2018. LCCN 2018000469 (print) | LCCN 2018000728 (ebook) |ISBN 9781119126836 (pdf) | ISBN 9781119126829 (epub) | ISBN 9781119126799 (pbk.) LCC RC271.C5 (ebook) | LCC RC271.C5 (print) | NLM QZ 267 |DDC 616.99/4061–dc23 LC record available at https://lccn.loc.gov/2018000469
2.A practical guide to cancer systems biology / Hsueh-Fen Juan, Hsuan-Cheng Huang, authors. New Jersey : World Scientific, [2017] LCCN 2017026929 | ISBN 9789813229143 LCC RC267 .J83 2017 | DDC 616.99/40072--dc23. LC record available at https://lccn.loc.gov/2017026929. World Scientific Publishing Co. Pte. Ltd.
3.The Biology of Cancer. Robert A. Weinberg, Gariand Science 2014
Weekly Detailed Course Contents
Week 1 - Theoretical & Practice
Introduction to Basic Oncology
Week 2 - Theoretical & Practice
Cancer Etiology
Week 3 - Theoretical & Practice
Cell Differentiation and Transformation
Week 4 - Theoretical & Practice
The Importance of Signal Pathways in Cancer
Week 5 - Theoretical & Practice
Cancer Related Genes: Oncogene and Tumor Suppressive Genes
Week 6 - Theoretical & Practice
The Importance of Staging in Cancer
Week 7 - Theoretical & Practice
Molecular Mechanisms in Special Cancer Types-1
Week 8 - Theoretical & Practice
Molecular Mechanisms in Special Cancer Types-2 (Midterm)
Week 9 - Theoretical & Practice
Cancer Genetic Changes: Mutations
Week 10 - Theoretical & Practice
DNA Damage and Repair in Cancer
Week 11 - Theoretical & Practice
Epigenetic Regulation and Changes in Cancer
Week 12 - Theoretical & Practice
Cancer and Immune System
Week 13 - Theoretical & Practice
Cancer Cell and Host Relations (Angiogenesis, Invasion and Metastasis)
Week 14 - Theoretical & Practice
Molecular Basics of Anticancer Therapy
Week 15 - Final Exam
Final
Assessment Methods and Criteria
Type of AssessmentCountPercent
Assignment1%5
Quiz1%5
Midterm Examination1%20
Final Examination1%70
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory140228
Lecture - Practice140228
Assignment1606
Quiz1011
Midterm Examination18210
Final Examination124226
TOTAL WORKLOAD (hours)99
Contribution of Learning Outcomes to Programme Outcomes
PÇ-1
PÇ-2
PÇ-3
PÇ-4
PÇ-5
PÇ-6
PÇ-7
PÇ-8
PÇ-9
PÇ-10
PÇ-11
PÇ-12
PÇ-13
PÇ-14
PÇ-15
OÇ-1
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
OÇ-2
4
4
4
5
5
4
5
5
5
5
5
5
5
5
5
OÇ-3
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
OÇ-4
5
5
5
5
5
5
5
4
4
4
5
5
5
5
5
OÇ-5
5
5
5
5
5
5
5
4
4
5
5
5
5
5
5
Adnan Menderes University - Information Package / Course Catalogue
2026