
| Course Code | : ONK605 |
| Course Type | : Required |
| Couse Group | : Third Cycle (Doctorate Degree) |
| Education Language | : Turkish |
| Work Placement | : N/A |
| Theory | : 2 |
| Prt. | : 2 |
| Credit | : 3 |
| Lab | : 0 |
| ECTS | : 4 |
To define basic oncology concepts, to understand the molecular basis of carcinogenesis and anticancer therapy with examples.
The aim of this course is to understand the relationship between carcinogenesis, cell cycle and cancer, differentiation, its role in transformation and cancer development and its molecular mechanisms. Cell death mechanisms, angiogenesis, invasion and metastasis, signal pathways in cancer, the importance of oncogene and tumor suppressor genes in cancer diagnosis, treatment and follow-up. In practice courses, cancer cell culture, Western Blot application, DNA from tumor tissue, RNA isolation, and real time PCR mutation analysis in cancer diagnosis will be discussed.
| 1. | To learn the basic oncological approach |
| 2. | To examine the carcinogenesis-tumogenesis steps |
| 3. | To discuss genetic changes and mutations in cancer. |
| 4. | Review of cancer-host and immune system relationships |
| 5. | To discuss anticancer treatment differences |
| 1. | A beginner’s guide to targeted cancer treatments / by Elaine Vickers. (Elaine Ruth), author. Hoboken, NJ : Wiley, 2018. LCCN 2018000469 (print) | LCCN 2018000728 (ebook) |ISBN 9781119126836 (pdf) | ISBN 9781119126829 (epub) | ISBN 9781119126799 (pbk.) LCC RC271.C5 (ebook) | LCC RC271.C5 (print) | NLM QZ 267 |DDC 616.99/4061–dc23 LC record available at https://lccn.loc.gov/2018000469 |
| 2. | A practical guide to cancer systems biology / Hsueh-Fen Juan, Hsuan-Cheng Huang, authors. New Jersey : World Scientific, [2017] LCCN 2017026929 | ISBN 9789813229143 LCC RC267 .J83 2017 | DDC 616.99/40072--dc23. LC record available at https://lccn.loc.gov/2017026929. World Scientific Publishing Co. Pte. Ltd. |
| 3. | The Biology of Cancer. Robert A. Weinberg, Gariand Science 2014 |
| Type of Assessment | Count | Percent |
|---|---|---|
| Assignment | 1 | %5 |
| Quiz | 1 | %5 |
| Midterm Examination | 1 | %20 |
| Final Examination | 1 | %70 |
| Activities | Count | Preparation | Time | Total Work Load (hours) |
|---|---|---|---|---|
| Lecture - Theory | 14 | 0 | 2 | 28 |
| Lecture - Practice | 14 | 0 | 2 | 28 |
| Assignment | 1 | 6 | 0 | 6 |
| Quiz | 1 | 0 | 1 | 1 |
| Midterm Examination | 1 | 8 | 2 | 10 |
| Final Examination | 1 | 24 | 2 | 26 |
| TOTAL WORKLOAD (hours) | 99 | |||
PÇ-1 | PÇ-2 | PÇ-3 | PÇ-4 | PÇ-5 | PÇ-6 | PÇ-7 | PÇ-8 | PÇ-9 | PÇ-10 | PÇ-11 | PÇ-12 | PÇ-13 | PÇ-14 | PÇ-15 | |
OÇ-1 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 |
OÇ-2 | 4 | 4 | 4 | 5 | 5 | 4 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 |
OÇ-3 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 |
OÇ-4 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 4 | 4 | 4 | 5 | 5 | 5 | 5 | 5 |
OÇ-5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 4 | 4 | 5 | 5 | 5 | 5 | 5 | 5 |