
| Course Code | : ONK607 |
| Course Type | : Area Elective |
| Couse Group | : Third Cycle (Doctorate Degree) |
| Education Language | : Turkish |
| Work Placement | : N/A |
| Theory | : 2 |
| Prt. | : 2 |
| Credit | : 3 |
| Lab | : 0 |
| ECTS | : 8 |
To give information about chemotherapy agents used as standard in cancer treatment and new treatment methods such as immunotherapy, biological, hormonal and targeted therapies.
The pharmacokinetics and pharmacodynamics of chemotherapy agents, alkylating agents, platinum analogues, antimetabolites, topoisomerase inhibitors, antimicrotubule agents, anti-Her2 agents, tyrosine kinase inhibitors, and their antiangiogenic agents in their individualized treatment will be described.
| 1. | Understand the mechanisms of action of chemotherapy agents used in cancer |
| 2. | Know which mutations direct treatment in which cancer |
| 3. | Know the treatment agents used in cancers with well-known kinase mutations |
| 4. | Knows in which cancers and under which conditions immunotherapies are used |
| 5. | Can analyze and plan studies on cancer treatment methods |
| 1. | -DeVita, Vincent T., Jr., Theodore S. Lawrence, and Steven A. Rosenberg. Devita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology. 10th edition. Philadelphia: Wolters Kluwer, 2015 |
| 2. | Akintunde Akinleye, Zoaib Rasool. Immune checkpoint inhibitors of PD-L1 as cancer therapeutics.Journal of Hematology & Oncologyvolume 12, : 92 (2019) |
| 3. | Pathologic Basis of Disease. Vinay Kumar, Abul K. Abbas, Nelson Fausto, Elsevier Saunderss, 2005 Seventh Edition |
| 4. | Molecular Mechanism of Cancer. Georg F. Weber, Springer 2007 |
| Type of Assessment | Count | Percent |
|---|---|---|
| Assignment | 1 | %5 |
| Quiz | 1 | %5 |
| Midterm Examination | 1 | %20 |
| Final Examination | 1 | %70 |
| Activities | Count | Preparation | Time | Total Work Load (hours) |
|---|---|---|---|---|
| Lecture - Theory | 14 | 1 | 2 | 42 |
| Lecture - Practice | 14 | 1 | 2 | 42 |
| Assignment | 1 | 24 | 1 | 25 |
| Quiz | 1 | 12 | 1 | 13 |
| Midterm Examination | 1 | 24 | 2 | 26 |
| Final Examination | 1 | 48 | 2 | 50 |
| TOTAL WORKLOAD (hours) | 198 | |||
PÇ-1 | PÇ-2 | PÇ-3 | PÇ-4 | PÇ-5 | PÇ-6 | PÇ-7 | PÇ-8 | PÇ-9 | PÇ-10 | PÇ-11 | PÇ-12 | PÇ-13 | PÇ-14 | PÇ-15 | |
OÇ-1 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 |
OÇ-2 | 5 | 5 | 5 | 3 | 2 | 1 | 1 | 1 | 5 | 5 | 5 | 5 | 5 | 5 | 5 |
OÇ-3 | 5 | 5 | 5 | 3 | 2 | 1 | 1 | 1 | 5 | 5 | 5 | 5 | 5 | 5 | 5 |
OÇ-4 | 5 | 5 | 5 | 3 | 2 | 1 | 1 | 1 | 5 | 5 | 5 | 5 | 5 | 5 | 5 |
OÇ-5 | 5 | 5 | 5 | 3 | 2 | 1 | 1 | 1 | 5 | 5 | 5 | 5 | 5 | 5 | 5 |