Information Package / Course Catalogue
Anticancer Chemotherapy and New Treatment Methods
Course Code: ONK607
Course Type: Area Elective
Couse Group: Third Cycle (Doctorate Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 2
Prt.: 2
Credit: 3
Lab: 0
ECTS: 8
Objectives of the Course

To give information about chemotherapy agents used as standard in cancer treatment and new treatment methods such as immunotherapy, biological, hormonal and targeted therapies.

Course Content

The pharmacokinetics and pharmacodynamics of chemotherapy agents, alkylating agents, platinum analogues, antimetabolites, topoisomerase inhibitors, antimicrotubule agents, anti-Her2 agents, tyrosine kinase inhibitors, and their antiangiogenic agents in their individualized treatment will be described.

Name of Lecturer(s)
Learning Outcomes
1.Understand the mechanisms of action of chemotherapy agents used in cancer
2.Know which mutations direct treatment in which cancer
3.Know the treatment agents used in cancers with well-known kinase mutations
4.Knows in which cancers and under which conditions immunotherapies are used
5.Can analyze and plan studies on cancer treatment methods
Recommended or Required Reading
1.-DeVita, Vincent T., Jr., Theodore S. Lawrence, and Steven A. Rosenberg. Devita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology. 10th edition. Philadelphia: Wolters Kluwer, 2015
2.Akintunde Akinleye, Zoaib Rasool. Immune checkpoint inhibitors of PD-L1 as cancer therapeutics.Journal of Hematology & Oncologyvolume 12, : 92 (2019)
3.Pathologic Basis of Disease. Vinay Kumar, Abul K. Abbas, Nelson Fausto, Elsevier Saunderss, 2005 Seventh Edition
4.Molecular Mechanism of Cancer. Georg F. Weber, Springer 2007
Weekly Detailed Course Contents
Week 1 - Theoretical & Practice
Clinical applications of chemotherapy
Week 2 - Theoretical & Practice
Pharmacokinetics and pharmacodynamics in anticancer drugs
Week 3 - Theoretical & Practice
Alkylating agents
Week 4 - Theoretical & Practice
Platinum analogs
Week 5 - Theoretical & Practice
Antimetabolites
Week 6 - Theoretical & Practice
Topoisomerase inhibitors
Week 7 - Theoretical & Practice
Antimicrotubule agents
Week 8 - Theoretical & Practice
Personalized Medicine in Cancer (Midterm)
Week 9 - Theoretical & Practice
Targeted therapy with tyrosine kinase inhibitors
Week 10 - Theoretical & Practice
Anti-angiogenic inhibitors
Week 11 - Theoretical & Practice
Monoclonal antibodies used in cancer treatment
Week 12 - Theoretical & Practice
Endocrine treatments used in cancer treatment
Week 13 - Theoretical & Practice
Use of immunotherapy in cancer
Week 14 - Theoretical & Practice
Evaluation of clinical response in cancer treatment
Week 15 - Final Exam
Final
Assessment Methods and Criteria
Type of AssessmentCountPercent
Assignment1%5
Quiz1%5
Midterm Examination1%20
Final Examination1%70
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory141242
Lecture - Practice141242
Assignment124125
Quiz112113
Midterm Examination124226
Final Examination148250
TOTAL WORKLOAD (hours)198
Contribution of Learning Outcomes to Programme Outcomes
PÇ-1
PÇ-2
PÇ-3
PÇ-4
PÇ-5
PÇ-6
PÇ-7
PÇ-8
PÇ-9
PÇ-10
PÇ-11
PÇ-12
PÇ-13
PÇ-14
PÇ-15
OÇ-1
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
OÇ-2
5
5
5
3
2
1
1
1
5
5
5
5
5
5
5
OÇ-3
5
5
5
3
2
1
1
1
5
5
5
5
5
5
5
OÇ-4
5
5
5
3
2
1
1
1
5
5
5
5
5
5
5
OÇ-5
5
5
5
3
2
1
1
1
5
5
5
5
5
5
5
Adnan Menderes University - Information Package / Course Catalogue
2026