Information Package / Course Catalogue
Precision Medicine and Treatment Methods in Cancer
Course Code: ONK608
Course Type: Area Elective
Couse Group: Third Cycle (Doctorate Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 2
Prt.: 2
Credit: 3
Lab: 0
ECTS: 8
Objectives of the Course

Based on targeted therapies and molecular features of cancer, individualizing medicine in cancer and understanding how the treatment is programmed specifically for the person and cancer

Course Content

Individualization of cancer treatment will be explained in the light of information and developments on targeted agents, molecular markers of cancer, resistance mechanisms in cancer, biological treatments, subtypes of certain cancers, factors that determine response to treatment in cancer.

Name of Lecturer(s)
Learning Outcomes
1.Recognizes cellular predictive and prognostic markers
2.Learns targeted therapeutic agents and mechanisms
3.Examine cellular therapy resistance mechanisms
4.Knows the personalized endocrine treatment principles in cancer.
5.Understands individualized treatment methods and principles in cancer
Recommended or Required Reading
1.A beginner’s guide to targeted cancer treatments / by Elaine Vickers. (Elaine Ruth), author. Hoboken, NJ : Wiley, 2018. LCCN 2018000469 (print) | LCCN 2018000728 (ebook) |ISBN 9781119126836 (pdf) | ISBN 9781119126829 (epub) | ISBN 9781119126799 (pbk.) LCC RC271.C5 (ebook) | LCC RC271.C5 (print) | NLM QZ 267 |DDC 616.99/4061–dc23 LC record available at https://lccn.loc.gov/2018000469
2.A practical guide to cancer systems biology / Hsueh-Fen Juan, Hsuan-Cheng Huang, authors. New Jersey : World Scientific, [2017] LCCN 2017026929 | ISBN 9789813229143 LCC RC267 .J83 2017 | DDC 616.99/40072--dc23. LC record available at https://lccn.loc.gov/2017026929. World Scientific Publishing Co. Pte. Ltd.
3.Small Molecules in Oncology. Third Edition. Uwe M. Martens Editor. ISSN 0080-0015 ISSN 2197-6767 (electronic). ISBN 978-3-319-91441-1 ISBN 978-3-319-91442-8 (eBook). https://doi.org/10.1007/978-3-319-91442-8. Springer International Publishing AG, part of Springer Nature 2018.
4.Gore L, DeGregori J, Porter CC. Targeting developmental pathways in children with cancer: what price success? Lancet Oncology 2013; 4(2):e70-78.
Weekly Detailed Course Contents
Week 1 - Theoretical & Practice
Predictive cellular markers in cancer-1
Week 2 - Theoretical & Practice
Predictive cellular markers in cancer-2
Week 3 - Theoretical & Practice
Prognostic cellular markers in cancer-1
Week 4 - Theoretical & Practice
Prognostic cellular markers in cancer-2
Week 5 - Theoretical & Practice
Treatment resistance mechanisms in cancer-2
Week 6 - Theoretical & Practice
Treatment resistance mechanisms in cancer-2
Week 7 - Theoretical & Practice
Principles of individualization of treatment in cancer-1
Week 8 - Theoretical & Practice
Principles of individualization of treatment in cancer-2 (Midterm)
Week 9 - Theoretical & Practice
Targeted molecular agents-1
Week 10 - Theoretical & Practice
Targeted molecular agents-2
Week 11 - Theoretical & Practice
Targeted endocrine treatments-1
Week 12 - Theoretical & Practice
Targeted endocrine treatments-2
Week 13 - Theoretical & Practice
Targeted biological agents-1
Week 14 - Theoretical & Practice
Targeted biological agents-2
Week 15 - Final Exam
Final
Assessment Methods and Criteria
Type of AssessmentCountPercent
Assignment1%5
Quiz1%5
Midterm Examination1%20
Final Examination1%70
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory141242
Lecture - Practice141242
Assignment124125
Quiz112113
Midterm Examination124226
Final Examination148250
TOTAL WORKLOAD (hours)198
Contribution of Learning Outcomes to Programme Outcomes
PÇ-1
PÇ-2
PÇ-3
PÇ-4
PÇ-5
PÇ-6
PÇ-7
PÇ-8
PÇ-9
PÇ-10
PÇ-11
PÇ-12
PÇ-13
PÇ-14
PÇ-15
OÇ-1
5
5
5
2
1
1
1
1
5
5
5
5
5
5
5
OÇ-2
5
5
5
2
1
1
1
1
5
5
5
5
5
5
5
OÇ-3
5
5
5
2
1
1
1
1
5
5
5
5
5
5
5
OÇ-4
5
5
5
2
1
1
1
1
5
5
5
5
5
5
5
OÇ-5
5
5
5
2
1
1
1
1
5
5
5
5
5
5
5
Adnan Menderes University - Information Package / Course Catalogue
2026