
| Course Code | : ONK617 |
| Course Type | : Area Elective |
| Couse Group | : Third Cycle (Doctorate Degree) |
| Education Language | : Turkish |
| Work Placement | : N/A |
| Theory | : 2 |
| Prt. | : 2 |
| Credit | : 3 |
| Lab | : 0 |
| ECTS | : 8 |
Factors that affect the DNA damage and development that occur in cancer, its mechanisms, DNA repair disorders and DNA damage in the formation and treatment of cancer.
Topics such as Free radical damage in cancer, DNA damage mechanisms in cancer development, base change repair of DNA damage, DNA damage and methods of determining repair mechanism disorders will be covered.
| 1. | Understands the identification of DNA damage and its types and the properties of the biological changes that occur. |
| 2. | Explain DNA repair mechanisms. |
| 3. | Knows and learns the DNA repair mechanisms and their role in cancer development. |
| 4. | Knows and learns the DNA repair mechanisms and their role in cancer treatment. |
| 5. | Examine the molecular properties of DNA damage and repair mechanism disorders and their reflection on the clinic in oncology. |
| 1. | Principles and Practise of Oncology 7th edition. Vincent T De Vita 2005. |
| 2. | Molecular Biology in Cancer Medicine. Razelle Kurzrock, Moshe Talpaz, Martin Dunitz 1995. |
| 3. | AJCC Cancer Staging Handbook.Irvin D. Fleming. Lippincott Willams & Wilkins 1998 |
| 4. | The Biology of Cancer Robert A. Weinberg, Gariand Science 2007 |
| Type of Assessment | Count | Percent |
|---|---|---|
| Assignment | 1 | %5 |
| Quiz | 1 | %5 |
| Midterm Examination | 1 | %20 |
| Final Examination | 1 | %70 |
| Activities | Count | Preparation | Time | Total Work Load (hours) |
|---|---|---|---|---|
| Lecture - Theory | 14 | 1 | 2 | 42 |
| Lecture - Practice | 14 | 1 | 2 | 42 |
| Assignment | 1 | 24 | 1 | 25 |
| Quiz | 1 | 8 | 1 | 9 |
| Midterm Examination | 1 | 24 | 2 | 26 |
| Final Examination | 1 | 48 | 2 | 50 |
| TOTAL WORKLOAD (hours) | 194 | |||
PÇ-1 | PÇ-2 | PÇ-3 | PÇ-4 | PÇ-5 | PÇ-6 | PÇ-7 | PÇ-8 | PÇ-9 | PÇ-10 | PÇ-11 | PÇ-12 | PÇ-13 | PÇ-14 | PÇ-15 | |
OÇ-1 | 5 | 5 | 5 | 3 | 2 | 2 | 2 | 2 | 5 | 5 | 5 | 5 | 5 | 3 | 5 |
OÇ-2 | 5 | 5 | 5 | 3 | 2 | 2 | 2 | 2 | 5 | 5 | 5 | 5 | 5 | 3 | 5 |
OÇ-3 | 5 | 5 | 5 | 3 | 2 | 2 | 2 | 2 | 5 | 5 | 5 | 5 | 5 | 3 | 5 |
OÇ-4 | 5 | 5 | 5 | 3 | 2 | 2 | 2 | 2 | 5 | 5 | 5 | 5 | 5 | 3 | 5 |
OÇ-5 | 5 | 5 | 5 | 3 | 2 | 2 | 2 | 2 | 5 | 5 | 5 | 5 | 5 | 3 | 5 |