Information Package / Course Catalogue
Advanced Clinical Toxicology Principles in Cancer Treatment
Course Code: ONK622
Course Type: Area Elective
Couse Group: Third Cycle (Doctorate Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 2
Prt.: 0
Credit: 2
Lab: 0
ECTS: 6
Objectives of the Course

To define the clinical toxicology concepts, to examine the side effects of agents used in cancer treatment and their management.

Course Content

Clinical Toxicology Concepts, Drug Development, Phase Studies, World Health Organization (WHO) Toxicity Scale, Chemotherapy Used in Cancer Treatment, Biological, Immunological and Molecular Target-oriented Agents, Toxicity, Side Effect Management and Side Effect Treatment.

Name of Lecturer(s)
Learning Outcomes
1.To learn the concepts of clinical toxicology
2.Understanding drug development stages and clinical phase studies
3.Learning to define World Health Organization toxicity scale
4.Review of toxicities of cancer drugs
5.To review side effect management and treatment in clinical toxicology
Recommended or Required Reading
1.Genetic Toxicology and Cancer Risk Assessment 1st Edition, ISBN-13: 978-0824702946
2.Translational Toxicology and Therapeutics: Windows of Developmental Susceptibility in Reproduction and Cancer, ISBN: 978-1-119-02360-9
Weekly Detailed Course Contents
Week 1 - Theoretical
Basic Concepts in Clinical Toxicology-1
Week 2 - Theoretical
Basic Concepts in Clinical Toxicology-2
Week 3 - Theoretical
Development of Cancer Drugs and Clinical Phase Studies-1
Week 4 - Theoretical
Development of Cancer Drugs and Clinical Phase Studies-2
Week 5 - Theoretical
World Health Organization (WHO) Toxicity Scale
Week 6 - Theoretical
Chemotherapy and Clinical Toxicity-1
Week 7 - Theoretical
Chemotherapy and Clinical Toxicity-2
Week 8 - Theoretical
Targeted Agents and Clinical Toxicity-1 (Midterm)
Week 9 - Theoretical
Hormonal Agents and Clinical Toxicity
Week 10 - Theoretical
Targeted Agents and Clinical Toxicity-2
Week 11 - Theoretical
Biological Agents and Clinical Toxicity
Week 12 - Theoretical
Immunological Agents and Clinical Toxicity
Week 13 - Theoretical
Clinical Toxicity Management
Week 14 - Theoretical
Treatment Principles in Toxicity Development
Week 15 - Final Exam
Final
Assessment Methods and Criteria
Type of AssessmentCountPercent
Assignment1%5
Quiz1%5
Midterm Examination1%20
Final Examination1%70
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory141242
Assignment118119
Quiz1819
Midterm Examination124226
Final Examination148250
TOTAL WORKLOAD (hours)146
Contribution of Learning Outcomes to Programme Outcomes
PÇ-1
PÇ-2
PÇ-3
PÇ-4
PÇ-5
PÇ-6
PÇ-7
PÇ-8
PÇ-9
PÇ-10
PÇ-11
PÇ-12
PÇ-13
PÇ-14
PÇ-15
OÇ-1
4
4
4
2
2
2
2
2
5
2
2
5
5
5
2
OÇ-2
4
4
4
2
2
2
2
2
5
5
5
5
5
2
5
OÇ-3
4
4
5
2
2
2
2
2
5
5
5
5
5
2
5
OÇ-4
4
4
5
2
2
2
2
2
5
5
5
5
5
2
5
OÇ-5
4
4
5
2
2
2
2
2
5
5
5
5
5
2
5
Adnan Menderes University - Information Package / Course Catalogue
2026