Information Package / Course Catalogue
Tumor Microenvironment
Course Code: ONK630
Course Type: Area Elective
Couse Group: Third Cycle (Doctorate Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 2
Prt.: 0
Credit: 2
Lab: 0
ECTS: 6
Objectives of the Course

To teach the tumor microenvironment, related cells and its relationship with cancer.

Course Content

Cells in the Tumor Microenvironment, Tumor Associated Macrophages, Tumor Associated Neutrophils, Cancer Associated Fibroblasts, Tumor Microenvironment as a Therapeutic Target in Cancer will be covered.

Name of Lecturer(s)
Learning Outcomes
1.Define tumor microenvironment
2.Knows cells in tumor microenvironment.
3.Explain the relationship of cells in tumor microenvironment with cancer.
4.Knows the relationship between ECM and tumor microenvironment.
5.Examines the therapeutic potential of the tumor microenvironment.
Recommended or Required Reading
1.Principles and Practise of Oncology 7th edition. Vincent T De Vita 2005
2.Cancer Medicine 6.th Edition (James Holland et al)
3.Molecular Biology in Cancer Medicine. Razelle Kurzrock, Moshe Talpaz, Martin Dunitz 1995.
Weekly Detailed Course Contents
Week 1 - Theoretical
Introduction to Tumor Microenvironment
Week 2 - Theoretical
Cells in the Tumor Microenvironment
Week 3 - Theoretical
T-lymphocytes and Tumor
Week 4 - Theoretical
B-lymphocytes and Tumor
Week 5 - Theoretical
Natural Killer Cells (NK) and Tumor
Week 6 - Theoretical
Tumor Associated Macrophages
Week 7 - Theoretical
Myeloid Originated Suppressor Cells
Week 8 - Theoretical
Tumor microenvironment models (Midterm)
Week 9 - Theoretical
Dendritic Cells
Week 10 - Theoretical
Tumor Associated Neutrophils
Week 11 - Theoretical
Cancer Associated Fibroblasts
Week 12 - Theoretical
Vascular Endothelial Cells and Pericytes
Week 13 - Theoretical
Extracellular Matrix and Microenvironment
Week 14 - Theoretical
Tumor Microenvironment as a Therapeutic Target in Cancer
Week 15 - Final Exam
Final
Assessment Methods and Criteria
Type of AssessmentCountPercent
Assignment1%5
Quiz1%5
Midterm Examination1%20
Final Examination1%70
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory141242
Assignment118119
Quiz1819
Midterm Examination124226
Final Examination148250
TOTAL WORKLOAD (hours)146
Contribution of Learning Outcomes to Programme Outcomes
PÇ-1
PÇ-2
PÇ-3
PÇ-4
PÇ-5
PÇ-6
PÇ-7
PÇ-8
PÇ-9
PÇ-10
PÇ-11
PÇ-12
PÇ-13
PÇ-14
PÇ-15
OÇ-1
5
5
5
2
2
2
2
2
5
5
5
5
5
2
5
OÇ-2
5
5
5
2
2
2
2
2
5
5
5
5
5
3
5
OÇ-3
5
5
5
5
2
2
2
2
5
5
5
5
5
1
5
OÇ-4
5
5
5
5
2
2
2
2
5
5
5
5
5
1
5
OÇ-5
5
5
5
2
2
2
2
2
5
5
5
5
5
1
5
Adnan Menderes University - Information Package / Course Catalogue
2026