Information Package / Course Catalogue
Radiobiology
Course Code: ONK637
Course Type: Area Elective
Couse Group: Third Cycle (Doctorate Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 2
Prt.: 0
Credit: 2
Lab: 0
ECTS: 6
Objectives of the Course

Teaching the fundamentals and principles of biologic effects of ionizing radiation on mammalian tissues. Radiation causes a process of events extending from microseconds to months and years after exposure. This course offers insight into the therapeutic and deleterious effects of irradiation.

Course Content

Introduction to Radiobiology: Basic Diagnosis and Concepts, General Features of Ionizing Radiation, Radiation Energy Distribution, LET and RBE Concepts, The Effect of Radiation on Nucleic Acids, Enzymes and Proteins, Cell Biology and the Effect of Radiation at the Cellular Level, Cell Death and Survival Curves, Factors Affecting Cellular Response, The Response to Radiation at the Cellular Level, The Effect of Radiation on Normal Tissues, The Effect of Radiation on Tumor Cells, Rationale of Whole Body Irradiation and Radiation Syndromes, Radiation Hazards and Biological Dosimetry, Radiation Protection and Safety Precautions

Name of Lecturer(s)
Learning Outcomes
1.To be able to understand cell biology
2.To understand the properties of ionizing radiation, to learn how ionizing radiation interacts with matter
3.Learning the effects of radiation on biological systems and understanding the acute and late effects of ionizing radiation
4.To understand the importance of radiobiology in tumor treatment with radiation
5.Learning the principles of radiation protection and taking safety precautions
Recommended or Required Reading
1.1. Basic Radiobiology, Atilla Özalpan Haliç Üniversitesi, ( 2001)
2.2. Radiobiology for the Radiologist, Eric Hall and Amato J. Giaccia. 8th Edition (2018)
3.3. Basic Clinical Radiobiology. Joiner MC, van der Kogel A (Editors) (2019)
Weekly Detailed Course Contents
Week 1 - Theoretical
Introduction to Radiobiology: Basic Diagnosis and Concepts
Week 2 - Theoretical
General Properties of Ionizing Radiation
Week 3 - Theoretical
Distribution of Radiation Energy, LET and RBE Concepts
Week 4 - Theoretical
The Effect of Radiation on Nucleic Acids, Enzymes and Proteins
Week 5 - Theoretical
Cell Biology and the Effect of Radiation at the Cellular Level
Week 6 - Theoretical
The Cell Death and Survival Curves
Week 7 - Theoretical
Factors Affecting the Cellular Response
Week 8 - Theoretical
Radiation Response at the Cellular Level-1 (Midterm Exam)
Week 9 - Theoretical
Radiation Response at the Cellular Level-2
Week 10 - Theoretical
The Effect of Ionizing Radiation on Normal Tissues
Week 11 - Theoretical
The Effect of Ionizing Radiation on Tumor Cells
Week 12 - Theoretical
The Rationale of Whole Body Irradiation and Radiation Syndromes
Week 13 - Theoretical
Radiation Hazards and Biological Dosimetry
Week 14 - Theoretical
Radiation Protection and Safety Precautions
Week 15 - Final Exam
Final Exam
Assessment Methods and Criteria
Type of AssessmentCountPercent
Attending Lectures1%5
Quiz1%5
Midterm Examination1%20
Final Examination1%70
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory141242
Assignment118119
Quiz1819
Midterm Examination124226
Final Examination148250
TOTAL WORKLOAD (hours)146
Contribution of Learning Outcomes to Programme Outcomes
PÇ-1
PÇ-2
PÇ-3
PÇ-4
PÇ-5
PÇ-6
PÇ-7
PÇ-8
PÇ-9
PÇ-10
PÇ-11
PÇ-12
PÇ-13
PÇ-14
PÇ-15
OÇ-1
4
2
2
3
4
2
OÇ-2
3
3
5
3
2
1
2
1
OÇ-3
3
2
2
3
2
2
2
3
2
OÇ-4
3
3
4
3
2
2
2
2
OÇ-5
5
5
5
3
3
3
Adnan Menderes University - Information Package / Course Catalogue
2026