Information Package / Course Catalogue
Enzyme Kinetics
Course Code: BİO608
Course Type: Area Elective
Couse Group: Third Cycle (Doctorate Degree)
Education Language: Turkish
Work Placement: N/A
Theory: 3
Prt.: 0
Credit: 3
Lab: 0
ECTS: 8
Objectives of the Course

To learn the properties, catalysis and kinetic properties of enzymes.

Course Content

Catalysis mechanisms, kinetics, factors affecting enzyme activity

Name of Lecturer(s)
Learning Outcomes
1.Learn and explain the kinetics of enzymes
2.Learns and explains enzyme mechanisms
3.Learns and explains the mechanisms that affect enzyme activity.
4.Learn and explain enzyme inhibition
5.Learn and explain allosteric enzymes
Recommended or Required Reading
1.Biyokimyanın Prensipleri (Lehninger), David L. Nelson & Michael M. Cox ; Nedret Kılıç, Palme Yayıncılık,2005
2.Biyokimya I, II, Engin Gözükara, Nobel Tıp Kitabevi, İstanbul, 1997
3.Enzymes, A Practical Introduction to Structure, Mechanism and Data Analysis, Robert A. Copeland, A. John Wiley and Sons Inc. Publication, 2000.
4.Enzyme Chemistry Impact and applications, C. J. Suckling, C. L. Gibson, A. R. Pitt, Blackie Academic and Professional, 1998
Weekly Detailed Course Contents
Week 1 - Theoretical
Structure and function of enzymes and proteins
Week 1 - Preparation Work
Structure and function of enzymes and proteins
Week 2 - Theoretical
Specificity of enzyme action
Week 2 - Preparation Work
Specificity of enzyme action
Week 3 - Theoretical
Monomeric and oligomeric enzymes
Week 3 - Preparation Work
Monomeric and oligomeric enzymes
Week 4 - Theoretical
Introduction to bioenergetics, catalysis and kinetics
Week 4 - Preparation Work
Introduction to bioenergetics, catalysis and kinetics
Week 5 - Theoretical
Kinetics of single-substrate enzyme-catalysed reactions
Week 5 - Preparation Work
Kinetics of single-substrate enzyme-catalysed reactions
Week 6 - Theoretical
Enzyme inhibitions
Week 6 - Preparation Work
Enzyme inhibitions
Week 7 - Theoretical
Kinetics of multi-substrate enzyme-catalysed reactions
Week 7 - Preparation Work
Kinetics of multi-substrate enzyme-catalysed reactions
Week 8 - Theoretical
Enzyme activity determination methods
Week 9 - Theoretical
The investigation of active side structure
Week 9 - Preparation Work
The investigation of active side structure
Week 10 - Theoretical
The chemical nature of enzyme catalysis
Week 10 - Preparation Work
The chemical nature of enzyme catalysis
Week 11 - Theoretical
The binding of ligands to proteins
Week 11 - Preparation Work
The binding of ligands to proteins
Week 12 - Theoretical
Sigmoidal kinetics and allosteric enzymes
Week 12 - Preparation Work
Sigmoidal kinetics and allosteric enzymes
Week 13 - Theoretical
Investigation of enzymes in biological preparations
Week 13 - Preparation Work
Investigation of enzymes in biological preparations
Week 14 - Theoretical
Extraction and purification of enzymes
Week 14 - Preparation Work
Extraction and purification of enzymes
Assessment Methods and Criteria
Type of AssessmentCountPercent
Midterm Examination1%30
Final Examination1%70
Workload Calculation
ActivitiesCountPreparationTimeTotal Work Load (hours)
Lecture - Theory143384
Assignment142142
Individual Work142256
Midterm Examination1426
Final Examination1426
TOTAL WORKLOAD (hours)194
Contribution of Learning Outcomes to Programme Outcomes
PÇ-1
PÇ-2
PÇ-3
PÇ-4
PÇ-5
OÇ-1
2
2
2
2
2
OÇ-2
2
2
2
2
2
OÇ-3
2
2
2
2
2
OÇ-4
2
2
2
2
2
OÇ-5
2
2
2
2
2
Adnan Menderes University - Information Package / Course Catalogue
2026